Search
Upadacitinib
go.drugbank.com/drugs/DB15091ApprovedInvestigationalMore recently, it has also been approved for the treatment of giant cell arteritis in adults and active polyarticular juvenile idiopathic arthritis in patients aged 2 years and older.[L10896] … Upadacitinib is an oral Janus kinase (JAK)1-selective inhibitor and a disease-modifying antirheumatic drug (DMARD) used in the treatment of rheumatoid arthritis to slow down disease progression.
Moxetumomab pasudotox
go.drugbank.com/drugs/DB12688ApprovedInvestigationalCD22 is a lineage-restricted B-cell antigen that is expressed solely in on B-chronic lymphocytic leukemia, hairy cell leukemia, acute lymphocytic leukemiathe and Burkitt's lymphoma. … [A38864] MxP appears as an improved form of BL22 by the mutation of the Fv region and the antibody phage-displayed. As well the residues SSY in the heavy chain are mutated to THW.
Edetate calcium disodium anhydrous
go.drugbank.com/drugs/DB14598ApprovedInvestigational[L12774] It is on the World Health Organization Model List of Essential Medicines.[A204173] Edetate calcium disodium was granted FDA approval on 16 July 1953.[L12774] … Edetate calcium disodium is a metal ion chelator used to reduce blood concentrations and depot stores of lead from the body.
Categories: Compounds used in a research, industrial, or household settingMilciclib Maleate
go.drugbank.com/drugs/DB16232InvestigationalMilciclib Maleate is under investigation in clinical trial NCT01301391 (Study of Oral PHA-848125AC in Patients With Malignant Thymoma Previously Treated With Multiple Lines of Chemotherapy).
Ezetimibe
go.drugbank.com/drugs/DB00973ApprovedInvestigationalThe discovery and research of this drug began in the early 1990s, after the intravenous administration of radiolabelled ezetimibe in rats revealed that it was being localized within enterocytes of the … [A33313] In genetically NPC1L1-deficient mice, a 70% reduction in intestinal cholesterol absorption was seen, and these mice were insensitive to ezetimibe treatment - it was determined based on these findings
Amsilarotene
go.drugbank.com/drugs/DB21085InvestigationalAmsilarotene is under investigation in clinical trial NCT00687596 (Study of TAC-101 as Second Line Treatment in Patients With Advanced Hepatocellular Carcinoma Who Received Sorafenib as First Line Therapy … Amsilarotene is a small molecule drug. The usage of the INN stem '-arotene' in the name indicates that Amsilarotene is a arotinoid derivative.
Baricitinib
go.drugbank.com/drugs/DB11817ApprovedInvestigational[L41760] Baricitinib was first approved by the European Commission (EC) in February 2017 for the treatment of rheumatoid arthritis in adults [A248395] and was later approved by the FDA in 2018. … Baricitinib is a Janus kinase (JAK) inhibitor. JAKs are tyrosine protein kinases that play an important role in pro-inflammatory signaling pathways.
Povidone
go.drugbank.com/drugs/DB11061ApprovedInvestigationalWithdrawnin eye drops. … It is also used in many technical applications with various roles as an adhesive, additive, and emulsifier.
Mixtures: i-Drops ARTIFICIAL TEARSCategories: Compounds used in a research, industrial, or household settingFenproporex
go.drugbank.com/drugs/DB01550ApprovedIllicitWithdrawnprescribed in South America. … In 2006 and 2009, the FDA issued warnings that it had been detected in diet pills sold online, and imported from foreign manufacturers.
Sotagliflozin
go.drugbank.com/drugs/DB12713ApprovedInvestigationalSotagliflozin is a dual inhibitor of SGLT1 and SGLT2, the first of its kind,[A244499] which is approved for use in the EU, in combination with insulin, to improve glycemic control in patients with type … [L39705] Its potency in inhibiting SGLT2 is similar to that of other SGLT2 inhibitors, such as [canagliflozin] and [dapagliflozin], but its potency in inhibiting SGLT1 is >10-fold higher than its predecessors
Categories: Drugs Used in Diabetes