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Displaying results 1721 - 1730 of 10000 in total
  1. Drug

    Rifampin

    go.drugbank.com/drugs/DB01045
    ApprovedInvestigational

    Rifampin, also known as rifampicin, is a broad-spectrum antimicrobial [A263748] that was first discovered in 1965 [A263753] and clinically used in 1968. … [A263768] Rifampin is used to treat tuberculosis and works by inhibiting the microbial DNA-dependent RNA polymerase (RNAP).[A263768]

    Synonyms: 5,6,9,17,19,21-Hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-8-[N-(4-methyl-1-piperazinyl)formimidoyl]-2,7-(epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan-1,11(2H)-dione 21-acetate, 3-(((4-Methyl-1-piperazinyl)imino)methyl)rifamycin SVMixtures: Rifoldin 300 mg mit INH Dragees, RINCURE ® 3 FDC TABLETAS CON PELICULA
  2. Drug

    Travoprost

    go.drugbank.com/drugs/DB00287
    ApprovedInvestigational

    [L49434] Unlike other prostaglandin analogues, travoprost demonstrates full agonism and high selectivity at the prostanoid receptor, reporting a higher efficacy in reducing intraocular pressure and a reduced … Travoprost is a synthetic isopropyl ester prodrug of a prostaglandin F2alpha (F2α) analogue and selective FP prostanoid receptor agonist.

    Synonyms: (1R-(1.ALPHA.(Z),2.BETA.(1E,3R*),3.ALPHA.,5.ALPHA.))-7-(3,5-DIHYDROXY-2-(3-HYDROXY-4-(3-(TRIFLUOROMETHYL)PHENOXY)-1-BUTENYL)CYCLOPENTYL)-5-HEPTENOIC ACID, 1-METHYLETHYL ESTER, isopropyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-{(1E,3R)-3-hydroxy-4-[(α,α,α-trifluoro-m-tolyl)oxy]-1-butenyl}cyclopentyl)-5-heptenoateInternational brands: Travo-Z
  3. Drug

    Cefadroxil

    go.drugbank.com/drugs/DB01140
    ApprovedInvestigationalVet approvedWithdrawn

    Long-acting, broad-spectrum, water-soluble, cephalexin derivative.

    Synonyms: D-CefadroxilCategories: Heterocyclic Compounds, 2-Ring
  4. Drug

    Bevacizumab

    go.drugbank.com/drugs/DB00112
    ApprovedInvestigational

    bevacizumab a therapeutic role in both oncology and ophthalmology. … [A192939,A192837,A192891,A193275] VEGF plays an important role in angiogenesis, lymphangiogenesis, and tumor growth, which are all factors that contribute to its attractiveness as a therapeutic target.

    Synonyms: 贝伐珠单抗, Bei Fa Zhu DankangInternational brands: Ai Rui Tuo, 安倍斯
  5. Indication

    Relapsed Multiple Myeloma

    go.drugbank.com/conditions/DBCOND0031510
    Drugs: Belantamab mafodotin · Carfilzomib · Ciltacabtagene autoleucel · Daratumumab · Dexamethasone · Elranatamab +8 more
    Synonyms: Multiple Myeloma in Relapse
  6. Indication

    Keratoconjunctivitis Sicca (KCS)

    go.drugbank.com/conditions/DBCOND0105777
    Drugs: Hydroxypropyl cellulose
    Synonyms: Keratoconjunctivitis sicca, in Sjögren syndrome, Keratoconjunctivitis sicca, in Sjogren's syndrome
  7. Drug

    Procainamide

    go.drugbank.com/drugs/DB01035
    Approved

    A derivative of procaine with less CNS action.

    Categories: Antiarrhythmics, Class I, Antiarrhythmics, Class IaSynonyms: p-Amino-N-(2-diethylaminoethyl)benzamide, p-Aminobenzoic diethylaminoethylamide
  8. Drug

    2-(1-(1-(2-chlorophenyl)-2-methoxy-2-oxoethyl)-4-sulfanyl-3-piperidinylidene) acetic acid

    go.drugbank.com/drugs/DB19221
    Investigational

    2-(1-(1-(2-chlorophenyl)-2-methoxy-2-oxoethyl)-4-sulfanyl-3-piperidinylidene) acetic acid is under investigation in clinical trial NCT03774394 (Impact of Chronic Kidney Disease on Clopidogrel Effects in

    Synonyms: 1-piperidineacetic acid, 3-(carboxymethylene)-.alpha.-(2-chlorophenyl)-4-mercapto-, 1-methyl ester, (.alpha.s,3z)-, 3-(carboxymethylene)-.alpha.-(2-chlorophenyl)-4-mercapto-1-piperidineacetic acid 1-methyl ester, (.alpha.s,3z)-
  9. Drug

    Trastuzumab

    go.drugbank.com/drugs/DB00072
    ApprovedInvestigational

    Produced in CHO cell cultures, trastuzumab is a recombinant IgG1 kappa, humanized monoclonal antibody [A40276] that selectively binds with high affinity in a cell-based assay (Kd = 5 nM) to the extracellular … [L14015] It is used as a treatment of human epidermal growth factor receptor (HER)-2+ metastatic breast cancer, where there is a proven amplification of the HER-2 oncogene or over-expression of the HER

    Mixtures: PHESGO® 600MG/600MG, PHESGO® 600MG/600MGCategories: HER2 (Human Epidermal Growth Factor Receptor 2) inhibitors
  10. Drug

    Hydrocortisone acetate

    go.drugbank.com/drugs/DB14539
    ApprovedInvestigationalVet approved

    Mixtures: Alcortin A, Alcortin ACategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 Inducers