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BQ-788
go.drugbank.com/drugs/DB17984InvestigationalSynonyms: D-norleucine, n-(((2r,6s)-2,6-dimethyl-1-piperidinyl)carbonyl)-4-methyl-l-leucyl-1-(methoxycarbonyl)-d-tryptophyl-, sodium salt (1:1)Mefenamic acid
go.drugbank.com/drugs/DB00784ApprovedA non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.
Categories: Anti-Inflammatory Agents, Non-Steroidal (Non-Selective), Analgesics, Non-NarcoticSynonyms: N-2,3-xylylanthranilic acid, N-(2,3-xylyl)-2-aminobenzoic acidDomperidone
go.drugbank.com/drugs/DB01184ApprovedInvestigationalVet approvedIt speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
Categories: Drugs for Functional Gastrointestinal DisordersProducts: Nu-domperidone 10 Mg TabletsNeuropeptide S receptor
go.drugbank.com/bio_entities/BE0000948TargetHumansG protein-coupled receptor for neuropeptide S (NPS) (PubMed:15947423, PubMed:16720571, PubMed:16790440). … Inhibits cell growth in response to NPS binding (PubMed:15947423)
Synonyms: G protein-coupled receptor for asthma susceptibilityThenalidine
go.drugbank.com/drugs/DB04826ApprovedWithdrawnWithdrawn from the Canadian, US, and UK markets in 1963 due to concerns involving neutropenia.
Categories: Antihistamines for Systemic Use, Antihistamines for Topical UseSynonyms: 1-Methyl-4-amino-N-phenyl-N-(2-thenyl)piperidine, 1-Methyl-4-N-2-thenylanilinopiperidineMargetuximab
go.drugbank.com/drugs/DB14967ApprovedInvestigational[A225751, A225756, A225766, A191829, L27986] Margetuximab binds to the same epitope on the HER2 extracellular domain and induces the same effects as [trastuzumab]. … [A225756] Margetuximab (formerly MGAH22) is an Fc-engineered human/mouse chimeric anti-HER2 IgG1κ monoclonal antibody derived from the same mouse 4D5 clone that [trastuzumab] is derived from and is
Brotizolam
go.drugbank.com/drugs/DB09017ApprovedWithdrawnBrotizolam is not approved for sale in the UK, United States or Canada but is sold in the Netherlands, Germany, Spain, Belgium, Austria, Portugal, Israel, Italy and Japan. … Brotizolam has similar effects to short-acting benzodiazepines such as triazolam. Brotizolam is indicated for 2-4 weeks of treatment for severe or debilitating insomnia.
Lithium cation
go.drugbank.com/drugs/DB01356ApprovedInvestigationalWithdrawnLithium can also be used to augment other antidepressant drugs. It is also sometimes prescribed as a preventive treatment for migraine disease and cluster headaches. … The active principle in these salts is the lithium ion Li+, which having a smaller diameter, can easily displace K+ and Na+ and even Ca+2, in spite of its greater charge, occupying their sites in several
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeSynonyms: Lithium ion, Lithium, ionTrimethoprim
go.drugbank.com/drugs/DB00440ApprovedInvestigationalVet approved[L11893] Trimethoprim is often used in combination with [sulfamethoxazole] due to their complementary and synergistic mechanisms but may be used as a monotherapy in the treatment and/or prophylaxis of … [L11893,L11830] It is structurally and chemically related to [pyrimethamine], another antifolate antimicrobial used in the treatment of plasmodial infections.[T707]
Mixtures: COMAZOLE N TABLET, Hampiseptol Solution For InjectionCategories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseTenofovir disoproxil
go.drugbank.com/drugs/DB00300ApprovedInvestigationalThis drug is prescribed in combination with other drugs for the management of HIV infection as well as for Hepatitis B therapy. Tenofovir disoproxil was initially approved in 2001 [FDA label]. … Tenofovir disoproxil fumarate (a prodrug of tenofovir), marketed by Gilead Sciences under the trade name _Viread_, belongs to a class of antiretroviral drugs known as nucleotide analogue reverse transcriptase
Mixtures: Symfi Lo, Symfi LoCategories: Antivirals used in combination for the treatment of HIV infections, Antivirals for Systemic Use