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Chlorambucil
go.drugbank.com/drugs/DB00291ApprovedInvestigationalA nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and nonmalignant diseases. … Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
Categories: Antineoplastic and Immunomodulating AgentsSynonyms: N,N-di-2-chloroethyl-γ-p-aminophenylbutyric acid, N,N-di-2-chloroethyl-gamma-p-aminophenylbutyric acidSqualene
go.drugbank.com/drugs/DB11460ApprovedInvestigationalVet approvedWithdrawnIt is ubiquitously distributed in human tissues where it is transported in serum generally in association with very low density lipoproteins. Squalene is investigated as an adjunctive cancer therapy. … It is not susceptible to lipid peroxidation and provides skin protection.
Mixtures: K-OMEGASQUA (Softgel)Products: SHINKAI SQUALENE 500mg Soft Gelatin CapsuleAspergillus oryzae
go.drugbank.com/drugs/DB10448ApprovedAspergillus oryzae allergenic extract is used in allergenic testing.
Products: Lactozyme - CapMetolazone
go.drugbank.com/drugs/DB00524ApprovedInvestigationalA quinazoline-sulfonamide that is considered a thiazide-like diuretic which is long-acting so useful in chronic renal failure. It also tends to lower blood pressure and increase potassium loss.
Categories: Genito Urinary System and Sex Hormones, metolazone and potassium-sparing agentsProducts: Zaroxolyn Tab 10mgOxolamine
go.drugbank.com/drugs/DB13216ApprovedOxolamine is not approved in the USA, it may be marketed elsewhere internationally as a cough suppressant [L5416]. It is listed as a prescription drug in New Zealand legislation [L5419]. … Oxolamine is also approved in Taiwan for the treatment of respiratory tract inflamation [L5422].
Mixtures: ASE-COLD 120 mg+50mg+1mg/5 ml PEDİATRİK ŞURUPCategories: Cough and Cold PreparationsEchinacea
go.drugbank.com/drugs/DB14240ApprovedCategories: Herbs and Natural ProductsProducts: Echinacea 500mg, Echinacea 500mg 50% Echinacea Angustifolia Root 50% Echinacea Purpurea RootCloprednol
go.drugbank.com/drugs/DB13843InvestigationalCloprednol is a synthetic glucocorticoid that has been investigated for use in the treatment of asthma. [A31775,A31776]
Categories: Sex Hormones and InsulinsProducts: SYNTESTAN 2.5MG, SYNTESTAN 5.0MGXylometazoline
go.drugbank.com/drugs/DB06694ApprovedXylometazoline is an imidazoline derivative [A228523] with sympathomimetic and nasal decongestant activity. … Xylometazoline works by binding to alpha (α)-adrenergic receptors to cause vasoconstriction of nasal blood vessels.
Categories: Decongestants and AntiallergicsProducts: Cold and Allergy Decongestant Nasal Spray, Otrivin Cold and Allergy Decongestant Nose DropsVarenicline
go.drugbank.com/drugs/DB01273ApprovedInvestigationalPfizer is conducting an additional safety study of the drug, results of which are expected in late 2015. … In addition it acts on alpha3/beta4 and weakly on alpha3beta2 and alpha6-containing receptors. A full agonism was displayed on alpha7-receptors. On March 9, 2015, the U.S.
Categories: Drugs Used in Addictive Disorders, Drugs Used in Nicotine DependenceProducts: CHAMPIX 1.0MG FILM-COATED TABLETSSodium- and chloride-dependent GABA transporter 1
go.drugbank.com/bio_entities/BE0000249TargetHumansCan also mediate sodium- and chloride-dependent transport of hypotaurine but to a much lower extent as compared to GABA (By similarity) … The translocation of GABA, however, may also occur in the reverse direction leading to the release of GABA (By similarity).
Polypeptides: Sodium- and chloride-dependent GABA transporter 1