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Dipyrithione
go.drugbank.com/drugs/DB11327Approved[A32829] Interestingly, dipyrithione has been studied and shown to have cytotoxic and potent broad-spectrum antitumor activity, which suggests a potential basis for an anticancer drug development. … [L2611] It is currently used as a pesticide, and not used in any FDA approved drug products.
Mixtures: Polytar AF ShampooIfosfamide
go.drugbank.com/drugs/DB01181ApprovedInvestigationalIfosfamide is a chemotherapeutic agent chemically related to the nitrogen mustards and a synthetic analog of cyclophosphamide. It is active as an alkylating agent and an immunosuppressive agent.
Categories: Cytochrome P-450 CYP2A6 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic IndexProducts: IFOSFAMIDA 1G POLVO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE., HOLOXAN 1 G IV İNFÜZYONLUK ÇÖZELTİ TOZU İÇEREN FLAKON, 1 ADETChlorzoxazone
go.drugbank.com/drugs/DB00356ApprovedIt is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202) … A centrally acting central muscle relaxant with sedative properties.
Mixtures: MEPADOL TABLET, 20 ADET, MUSKAZON TABLET, 20 ADETProducts: PARAFLEX 250 MG TABLET, 20 ADET, PARAFLEX 250 MG TABLET, 500 ADETGlymidine
go.drugbank.com/drugs/DB01382ApprovedGlycodiazine is used with diet to lower blood glucose by increasing the secretion of insulin from pancreas and increasing the sensitivity of peripheral tissues to insulin. … The mechanism of action of glycodiazine in lowering blood glucose appears to be dependent on stimulating the release of insulin from functioning pancreatic beta cells, and increasing sensitivity of peripheral
Categories: combinations of sulfonamidesBromothalonil
go.drugbank.com/drugs/DB14199ApprovedBromothalonil, also known as Methyldibromo glutaronitrile (MDBGN), is a widely used preservative that can be found in many personal hygiene and industrial products. … It is also a known allergen and dermatological irritant that has been banned in many EU countries due to increasing rates of contact allergy [A34322].
Categories: Compounds used in a research, industrial, or household settingAlanosine
go.drugbank.com/drugs/DB05540InvestigationalAn amino acid analogue and antibiotic derived from the bacterium Streptomyces alanosinicus with antimetabolite and potential antineoplastic activities.
Categories: Compounds used in a research, industrial, or household settingLefamulin
go.drugbank.com/drugs/DB12825ApprovedA pleuromotilin is a more recently developed type of antibiotic that is derived from the fungus, Pleurotus mutilus. … Lefamulin is a pleuromutilin antibiotic used for the treatment of bacterial community-acquired pneumonia.
Scopolamine
go.drugbank.com/drugs/DB00747ApprovedInvestigational[A228763] As an acetylcholine analogue, scopolamine can antagonize muscarinic acetylcholine receptors (mAChRs) in the central nervous system and throughout the body, inducing several therapeutic and adverse … [A228423, A228758] As a result of its anticholinergic effects, scopolamine is being investigated for diverse therapeutic applications; currently, it is approved for the prevention of nausea and vomiting
Lithium cation
go.drugbank.com/drugs/DB01356ApprovedInvestigationalWithdrawnLithium can also be used to augment other antidepressant drugs. It is also sometimes prescribed as a preventive treatment for migraine disease and cluster headaches. … The active principle in these salts is the lithium ion Li+, which having a smaller diameter, can easily displace K+ and Na+ and even Ca+2, in spite of its greater charge, occupying their sites in several
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeHuman papillomavirus type 6 L1 capsid protein antigen
go.drugbank.com/drugs/DB10299ApprovedInvestigationalIt is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) types 6, 11, 16 and 18. … The vaccine is prepared from the purified virus-like particles (VLPs) of the major capsid (L1) protein of HPV Types 6, 11, 16, and 18, which are produced by separate fermentations in recombinant *Saccharomyces
Mixtures: GARDASIL® 9 VACUNA RECOMBINANTE NONAVALENTE CONTRA EL VIRUS DEL PAPILOMA HUMANO, GARDASIL® 9 VACUNA RECOMBINANTE NONAVALENTE CONTRA EL VIRUS DEL PAPILOMA HUMANO