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Colestipol
go.drugbank.com/drugs/DB00375Approved[FDA Label, F4555, F4567, L6262] In particular, as colestipol's general mechanism of action ultimately results in the decreased absorption and enhanced secretion of bile acids and lipids in the feces … Bile acid sequestrants like colestipol have been in use since the 1970s.
Categories: Compounds used in a research, industrial, or household settingRezafungin
go.drugbank.com/drugs/DB16310ApprovedInvestigational[L45633,L45658] It was subsequently approved in the EU in November of the same year. [L52745] … Rezafungin has a half-life higher than 130 hours and can be administered once a week instead of daily.
Synonyms: Rezafungin ion, Echinocandin B, 1-((4R,5R)-4-hydroxy-N2-((4''-(pentyloxy)(1,1':4',1''-terphenyl)-4-yl)carbonyl)-5-(2-(trimethylammonio)ethoxy)-l-ornithine)-4-((4S)-4-hydroxy-4-(4-hydroxyphenyl)-l-allothreonine)-Regdanvimab
go.drugbank.com/drugs/DB16405ApprovedWithdrawnTrials investigating the use of regdanvimab as a therapeutic candidate for the treatment of COVID-19 began in mid-2020. … [A235830,A241995] It received its first full approval in South Korea in September 2021,[A241995] followed by the EU in November 2021.[L39130]
Buprenorphine
go.drugbank.com/drugs/DB00921ApprovedIllicitInvestigationalVet approvedClinically, this results in a slow onset of action and a clinical phenomenon known as the "ceiling effect" where once a certain dose is reached, buprenorphine's effects plateau. … [L46571] Buprenorphine is commercially available as the brand name product Suboxone which is formulated in a 4:1 fixed-dose combination product along with [naloxone], a non-selective competitive opioid
Categories: Drugs Used in Opioid Dependence, Drugs Used in Addictive DisordersSynonyms: 2-(N-cyclopropylmethyl-4,5α-epoxy-3-hydroxy-6-methoxy-6,14-endo-ethanomorphinan-6α-yl)-3,3-dimethyl-2-butanolDexrazoxane
go.drugbank.com/drugs/DB00380ApprovedInvestigationalWithdrawnIt appears to inhibit formation of a toxic iron-anthracycline complex. … [PubChem] The Food and Drug Administration has designated dexrazoxane as an orphan drug for use in the prevention or reduction in the incidence and severity of anthracycline-induced cardiomyopathy.
Categories: Compounds used in a research, industrial, or household setting, Topoisomerase II InhibitorsPiretanide
go.drugbank.com/drugs/DB02925ApprovedPiretanide (INN, trade names Arelix, Eurelix, Tauliz) has been synthesized in 1973 at Hoechst AG (Germany) as a loop diuretic compound by using a then-new method for introducing cyclic amine residues in … an aromatic nucleus in the presence of other aromatically bonded functional groups.
Mixtures: RAMITANID AL 5MG/6MG, RAMIPRIL PIRETA 1A PHA 5/6Products: PIRETANID 3 1A PHARMA, PIRETANID 6 1A PHARMAPramocaine
go.drugbank.com/drugs/DB09345ApprovedPramocaine is available by itself and in combination with other medications in various topical preparations. … Pramocaine (also known as pramoxine or pramoxine HCI) is a topical anesthetic and antipruritic.
Mixtures: Pomada De La Campana Triple Antibiotic Pain Relief, L-Topical CALAMINE 8% PRAMOXINE HCL 1%Products: First On Topical Analgesic, Bikini Zone Medicated After-shave Roll-ON ReliefCalcium carbimide
go.drugbank.com/drugs/DB09116ApprovedWithdrawnCalcium carbimide was conceived as an alternative for the treatment of alcoholism with a reduced side effect profile either when it is consumed accompanied by alcohol or without it. … [A31516] This drug was developed by Lederle Cyanamid Canada Inc and approved for marketing in Canada in 1959. The current status of calcium carbimide is cancelled post marketing.[L1113]
Categories: Drugs Used in Addictive Disorders, Drugs Used in Alcohol DependenceParoxetine
go.drugbank.com/drugs/DB00715ApprovedInvestigationalParoxetine is well tolerated in most patients with a similar adverse effect profile to other members of its drug class. … [L7712,L7715] A unique feature of this drug is that it is highly potent and selective in its inhibition of serotonin reuptake and has little effect on other neurotransmitters.
Products: PAROXETIN 1A PHARMA 10MG, PAROXETIN 1A PHARMA 20MGDiphenoxylate
go.drugbank.com/drugs/DB01081ApprovedIllicitInvestigationalWhen diphenoxylate is used alone, it is classified as a Schedule II. … A meperidine congener used as an antidiarrheal, usually in combination with atropine. At high doses, it acts like morphine.
Mixtures: PHARMANIAGA DIPHENOXYLATE A TABLET