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Displaying results 1751 - 1760 of 10000 in total
  1. Drug

    Norethisterone

    go.drugbank.com/drugs/DB00717
    ApprovedInvestigational

    [A10367] Norethisterone mimics the actions of endogenous [progesterone], albeit with a greater potency,[A188075] and is used on its own or in combination with estrogen derivatives in a variety of applications … Norethisterone, also known as norethindrone, is a synthetic progestational hormone belonging to the 19-nortestosterone-derived class of progestins.

    Synonyms: 17-hydroxy-19-nor-17-α-pregn-4-en-20-yn-3-one, 17-β-hydroxy-19-norpregn-4-en-20-yn-3-oneInternational brands: Primolut-N
  2. Drug

    Tiapride

    go.drugbank.com/drugs/DB13025
    Investigational

    Tiapride is a selective D2 and D3 dopamine receptor blocker in the brain.

    Products: TIADAL 100 MG/2 ML AMPUL, 12 ADET, TIADAL 100 MG TABLET, 20 ADET
  3. Drug

    Febuxostat

    go.drugbank.com/drugs/DB04854
    ApprovedInvestigational

    Febuxostat is a non-purine xanthine oxidase (XO) inhibitor. … [A39743] In early 2008, febuxostat was granted marketing authorization by the European Commission for the treatment of chronic hyperuricemia and gout.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesSynonyms: 2-(3-cyano-4-isobutoxyphenyl)-4-methyl- 1,3-thiazole-5-carboxylic acid
  4. Drug

    Cobamamide

    go.drugbank.com/drugs/DB11191
    ApprovedNutraceutical

    This drug is available as a nutritional supplement to prevent vitamin B12 deficiency. Vitamin B12 is a collective term for these variously substituted corrinoids. … There has been a shift in the treatment of vitamin B12 deficiency such that MeCbl is being extensively used and promoted.

    Synonyms: 5'-Deoxy-5'-adenosylcobalamin, Coenzyme B-12Mixtures: EnLyte Extra-LN
  5. Drug

    Calcium ascorbate

    go.drugbank.com/drugs/DB14483
    ApprovedNutraceutical

    Synonyms: L-ascorbic acid, calcium salt (2:1)Mixtures: Ester-C 500 mg, Ester-C 500 mg
  6. Drug

    Lolium perenne pollen

    go.drugbank.com/drugs/DB10389
    Approved

    Lolium perenne pollen is the pollen of the Lolium perenne plant. Lolium perenne pollen is mainly used in allergenic testing.

    Mixtures: SLITone ULTRA D. glomerata/ L. perenne/ P. pratense/ P. pratensis/ A. odoratum, Oralair 100 IRProducts: Standardized Grass Pollen - Perennial Ryegrass (100 Bau/ml), Center-AL - Lolium Perenne Pollen
  7. Drug

    Protionamide

    go.drugbank.com/drugs/DB12667
    ApprovedInvestigationalWithdrawn

    Prothionamide has been used in trials studying the treatment of MDR-TB and HIV Infections.

    Categories: Heterocyclic Compounds, 1-RingProducts: TIONAMID 250 MG DRAJE, 500 ADET, TIONAMID 250 MG DRAJE, 50 ADET
  8. Drug

    Warfarin

    go.drugbank.com/drugs/DB00682
    ApprovedInvestigational

    Although originally marketed as a pesticide (d-Con, Rodex, among others), Warfarin has since become the most frequently prescribed oral anticoagulant in North America. … Warfarin is an anticoagulant drug normally used to prevent blood clot formation as well as migration.

    Synonyms: 4-Hydroxy-3-(3-oxo-1-phenylbutyl)coumarinCategories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2C18 Substrates with a Narrow Therapeutic Index
  9. Drug

    Tizanidine

    go.drugbank.com/drugs/DB00697
    ApprovedInvestigational

    Tizanidine is a fast-acting drug used for the management of muscle spasm, which may result from the effects of multiple sclerosis, stroke, an acquired brain injury, or a spinal cord injury [T574]. … Initially approved by the FDA in 1996, tizanidine is an Alpha-2 adrenergic receptor agonist reducing spasticity by the presynaptic inhibition of excitatory neurotransmitters that cause firing of neurons

    Synonyms: 5-Chloro-4-(2-imidazolin-2-ylamino)-2,1,3-benzothiadiazoleInternational brands: Sirdalud MR
  10. Drug

    Lapatinib

    go.drugbank.com/drugs/DB01259
    ApprovedInvestigational

    Lapatinib is an anti-cancer drug developed by GlaxoSmithKline (GSK) as a treatment for solid tumours such as breast and lung cancer. … Lapatinib is a human epidermal growth factor receptor type 2 (HER2/ERBB2) and epidermal growth factor receptor (HER1/EGFR/ERBB1) tyrosine kinases inhibitor.

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: N-(3-chloro-4-((3-fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-4-quinazolinamine