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Displaying results 1751 - 1760 of 10000 in total
  1. Drug

    Bordetella pertussis toxoid antigen (formaldehyde inactivated)

    go.drugbank.com/drugs/DB14388
    ApprovedInvestigational

    Bordetella pertussis toxoid antigen (formaldehyde inactivated) is a vaccine.

    Mixtures: -POLIO SUSPENSION FOR INJECTION IN PRE-FILLED SYRINGE, Repevax Injektionssuspension in einer FertigspritzeSynonyms: Bordetella Pertussis Toxoid Antigen, C
  2. Target

    Carbonyl reductases (CBRs)

    go.drugbank.com/bio_entities/BE0010129
    EnzymeHumans

    Can convert prostaglandin E to prostaglandin F2-alpha (By similarity). Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. … weak agonists of NR3C1 and NR3C2 in adipose tissue (PubMed:28878267)

    Synonyms: Prostaglandin-E(2) 9-reductase
  3. Drug

    Eteplirsen

    go.drugbank.com/drugs/DB06014
    ApprovedInvestigational

    It consists of a six-membered morpholino ring replacing the five-membered ribofuranosyl rings found in natural DNA and RNA. … Eteplirsen was first approved by the FDA in September 2016 for the treatment of Duchenne muscular dystrophy (DMD) in patients with a confirmed mutation of the DMD gene, which codes for dystrophin, that

    Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 1-RingSynonyms: )-1-piperazinyl)-N,N-dimethylphosphonamidate) RNA, (P-deoxy-P-(dimethylamino)](2',3'-dideoxy-2',3'-imino-2',3'-seco)(2'a→5')(C-m5U-C-C-A-A-C-A-m5U-C-A-A-G-G-A-A-G-A-m5U-G-G-C-A-m5U-m5U-m5U-C-m5U-A-G),5'-(P-(4-((2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)carbonyl
  4. Drug

    Galactose

    go.drugbank.com/drugs/DB11735
    ApprovedInvestigationalWithdrawn

    As a naturally occurring sugar, it may be found in a number dairy products. Even then, however, it is not generally used as a sweetener considering it is only about 30% as sweet as sucrose. … Regardless, although it is predominantly used as a pathway to generate glucose fuel for the human body, galactose is involved as an ingredient in some commonly used vaccines and non-prescription products

    Mixtures: Levovist - Pws IV (4g Granules /vial)Synonyms: D-Galactose, D(+)-Galactose
  5. Drug

    Vanadium

    go.drugbank.com/drugs/DB13971
    Approved

    Mixtures: Multi Plex I - Tab, C. Vit-min Formula
  6. Drug

    Calcium glycerophosphate

    go.drugbank.com/drugs/DB11264
    Approved

    It is also present in dental or oral hygiene products due to its cariostatic effects. … By FDA, calcium glycerophosphate is considered a generally recognized as safe (GRAS) food ingredient as a nutrient supplement (source of calcium or phosphorus), or in food products such as gelatins, puddings

    Mixtures: Calcium Inj, Alsimine W Vitamins A DSynonyms: calcium β-glycerophosphate, β-glycerophosphoric acid calcium salt
  7. Drug

    Acamprosate

    go.drugbank.com/drugs/DB00659
    ApprovedInvestigational

    It is a structural analogue of the neurotransmitter γ-aminobutyric acid (GABA). … It was first approved by the FDA in 2004 and initially marketed by Forest Laboratories.[L31783]

    Categories: Drugs Used in Addictive Disorders, Drugs Used in Alcohol DependenceSynonyms: N-Acetylhomotaurine, N-acetyl homotaurine
  8. Pathway

    Difluprednate Action Pathway

    smpdb.ca/view/SMP0126254
    Drug action

    In the eyes, it is therefore deacetylated in the aqueous humor to difluoroprednisolone butyrate (DFB), the drug’s active metabolite.

    Drugs: Glutathione · Dinoprostone · Calcium · Prostaglandin D2 · Mesoheme · Prostaglandin G2 +2 more
    Enzymes: Prostaglandin E synthase
  9. Drug

    Meradimate

    go.drugbank.com/drugs/DB11096
    Approved

    Meradimate, before known as menthyl anthranilate, is used in a maximal concentration of 5% in different products as a UV filter. … [T200] It is currently required to be named as meradimate in all FDA approved OTC products. Meradimate is approved by the FDA and Health Canada to be used as an ingredient in sunblocking products.

    Mixtures: Body Armor Sun 'n Bug Block, SPF 15 Spray-ON SunscreenSynonyms: Menthyl-O-aminobenzoate
  10. Drug

    Dacomitinib

    go.drugbank.com/drugs/DB11963
    ApprovedInvestigational

    Dacomitinib, designed as (2E)-N-16-4-(piperidin-1-yl) but-2-enamide, is an oral highly selective quinazalone part of the second-generation tyrosine kinase inhibitors which are characterized by the irreversible … [L4810] Some evidence in the literature suggests the therapeutic potential of dacomitinib in the epithelial ovarian cancer model[A39624], although further investigations are needed.

    Categories: Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic Index