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Sodium/potassium-transporting ATPase subunit beta-2
go.drugbank.com/bio_entities/BE0005018TransporterTargetHumansThis is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-2 subunit is not known
Synonyms: Adhesion molecule in gliaGlycogen phosphorylase, muscle form
go.drugbank.com/bio_entities/BE0000916TargetHumansAllosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular
Polypeptides: Glycogen phosphorylase, muscle formGlycogen phosphorylase, brain form
go.drugbank.com/bio_entities/BE0002150TargetHumansEnzymes from different sources differ in their regulatory mechanisms and in their natural substrates (PubMed:3346228). … Phosphorylase is an important allosteric enzyme in carbohydrate metabolism (PubMed:3346228).
Polypeptides: Glycogen phosphorylase, brain formMepyramine
go.drugbank.com/drugs/DB06691ApprovedVet approvedIt has been found in over-the-counter combination products for colds and menstrual symptoms, but is considered to be an unapproved prescription medication used for cough, cold, or allergic conditions. … Mepyramine, or pyrilamine, targets the H1 receptor. It is a first generation antihistamine. However, it rapidly permeates the brain and so often causes drowsiness as a side effect.
Mixtures: Bronchodex Fort-DM Syr, Neo ACCategories: Antihistamines for Systemic Use, Antihistamines for Topical UseDiphenylpyraline
go.drugbank.com/drugs/DB01146ApprovedDiphenylpyraline is an antihistamine. Antihistamines used in the treatment of allergy act by competing with histamine for H 1-receptor sites on effector cells. … Antihistamines prevent, but do not reverse, responses mediated by histamine alone.
Mixtures: Eucillin "B" - Salbe, Emercreme No4 Ont EfaCategories: Antihistamines for Systemic UseBalsam of Peru
go.drugbank.com/drugs/DB11482ApprovedNutraceuticalVet approvedas safe (GRAS). … [F117] Under the FDA, balsam of Peru is considered as an inactive ingredient to be used for approved drug products[L2878] as well as an approved food additive under the categorization of generally recognized
Mixtures: Keloid Healer Synergy for treatment of keloids, Stroke II SynergyCategories: Compounds used in a research, industrial, or household settingBupropion
go.drugbank.com/drugs/DB01156ApprovedInvestigational[A6399,A178810] Bupropion was originally classified as an "atypical" antidepressant because it does not exert the same effects as the classical antidepressants such as Monoamine Oxidase Inhibitors ( … [F4624] When used in combination with [naltrexone] in the marketed product ContraveⓇ for chronic weight management, the two components are thought to have effects on areas of the brain involved in the
Categories: Antidepressive Agents Indicated for DepressionProducts: BUDEP XR® TABLETAS, WELLBUTRIN XR 150 MGRezafungin
go.drugbank.com/drugs/DB16310ApprovedInvestigational[A258403] In March 2023, the FDA approved rezafungin for injection for the treatment of candidemia and invasive candidiasis in adults with limited or no alternative treatment options. … [L45633,L45658] It was subsequently approved in the EU in November of the same year. [L52745]
Synonyms: Rezafungin ion, Echinocandin B, 1-((4R,5R)-4-hydroxy-N2-((4''-(pentyloxy)(1,1':4',1''-terphenyl)-4-yl)carbonyl)-5-(2-(trimethylammonio)ethoxy)-l-ornithine)-4-((4S)-4-hydroxy-4-(4-hydroxyphenyl)-l-allothreonine)-Asparaginase Erwinia chrysanthemi
go.drugbank.com/drugs/DB08886ApprovedInvestigational[A236344] Studies show that substitution of _Erwinia_ asparaginase for _E. coli_-derived asparaginase following an allergic reaction has been safe and effective. … [L149] In June 2021, the recombinant form of asparaginase _Erwinia chrysanthemi_ was approved by the FDA as a component of a chemotherapy regimen to treat acute lymphoblastic leukemia and lymphoblastic