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Isoflavone
go.drugbank.com/drugs/DB12007ApprovedInvestigationalWithdrawnIsoflavone is a soy phytoestrogen and a biologically active component of several agriculturally important legumes such as soy, peanut, green peas, chick peas and alfalfa [A33103]. … Isoflavone is found as one of constituents in oral over-the-counter dietary supplements indicated for improved bone mass density and body fat regulation.
Tislelizumab
go.drugbank.com/drugs/DB14922ApprovedInvestigational[L49439] Tislelizumab was also approved by the FDA on March 14, 2024.[L50346] It has subsequently been approved for additional cancers in the US and EU. [L49349] … It was engineered to have a nullified Fc portion, thus minimizing binding to FcγR on macrophages and limiting treatment resistance via antibody-dependent phagocytosis.
Hexachlorophene
go.drugbank.com/drugs/DB00756ApprovedWithdrawnIt is mainly used in soaps and creams and is an ingredient of various preparations used for skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p797)
International brands: E-Z scrubPlazomicin
go.drugbank.com/drugs/DB12615ApprovedIt is marketed as Zemdri and is administered via once-daily intravenous infusion. … The structure of plazomicin was established via appending hydroxylaminobutyric acid to [DB12604] at position 1 and 2-hydroxyethyl group at position 6' [A33942].
Almasilate
go.drugbank.com/drugs/DB13595ApprovedHowever its therapeutic efficacy is not comparable to other approved antacids, as it is no more effective in neutralizing acid and binding bile salts than other conventional antacids [A27138]. … Almasilate is a buffering antacid that has been used in peptic ulcers and dyspepsia.
Beclamide
go.drugbank.com/drugs/DB09011ExperimentalIt was studied in the 1950s for generalised tonic-clonic seizures but was not effective for absence seizures.
Setmelanotide
go.drugbank.com/drugs/DB11700ApprovedInvestigational[A224449] Imcivree was granted EMA orphan designation on November 19, 2018 [L24559] and FDA approval on November 25, 2020.[L24429] On May 4, 2023, it was approved by Health Canada.[L46327] … [A224449] Earlier attempts at agonizing MC4R (such as LY2112688) lead to successful weight loss, but also an increase in blood pressure and heart rate.
Sodium carbonate
go.drugbank.com/drugs/DB09460ApprovedWithdrawnAs a strong base, sodium hydroxide neutralizes gastric acid thereby acting as an antacid.
Mupirocin
go.drugbank.com/drugs/DB00410ApprovedInvestigationalVet approved[L10580] It primarily works by inhibiting bacterial protein synthesis. … Due to its unique mode of action of inhibiting the activity of bacterial isoleucyl-tRNA synthetase, mupirocin does not demonstrate cross-resistance with other classes of antimicrobial agents, giving it
Mixtures: Dermawerx Surgical Plus PakSynonyms: 9-[(E)-4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-[[(2S,3S)-3- [(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl]methyl] oxan-2-yl]-3-methylbut-2-enoyl]oxynonanoic acidSynthetic camphor
go.drugbank.com/drugs/DB14156ApprovedMixtures: Arex Sinsin Pas, Arex Sinsin PasProducts: Rite Aid Pharmacy congestion relief vaporizing steam