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Displaying results 1771 - 1780 of 10000 in total
  1. Drug

    Rezafungin

    go.drugbank.com/drugs/DB16310
    ApprovedInvestigational

    [A258403] In March 2023, the FDA approved rezafungin for injection for the treatment of candidemia and invasive candidiasis in adults with limited or no alternative treatment options. … [L45633,L45658] It was subsequently approved in the EU in November of the same year. [L52745]

    Synonyms: Rezafungin ion, Echinocandin B, 1-((4R,5R)-4-hydroxy-N2-((4''-(pentyloxy)(1,1':4',1''-terphenyl)-4-yl)carbonyl)-5-(2-(trimethylammonio)ethoxy)-l-ornithine)-4-((4S)-4-hydroxy-4-(4-hydroxyphenyl)-l-allothreonine)-
  2. Drug

    Tropicamide

    go.drugbank.com/drugs/DB00809
    Approved

    [A229958] It is also used in combination with [hydroxyamphetamine] for the same indication. … [A230103] Usually available in ophthalmic formulations, tropicamide is used to cause mydriasis and cycloplegia for eye exams or ocular procedures.

  3. Drug

    Pentazocine

    go.drugbank.com/drugs/DB00652
    ApprovedVet approved

    The first mixed agonist-antagonist analgesic to be marketed. It is an agonist at the kappa and sigma opioid receptors and has a weak antagonist action at the mu receptor.

    Mixtures: TALWIN NxCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  4. Drug

    Mipomersen

    go.drugbank.com/drugs/DB05528
    Approved

    Mipomersen sodium, which was known as the investigational drug, isis-301012, is the salt form of a synthetic phosphorothioate oligonucleotide. … Mipomersen is indicated in patients with homozygous familial hypercholesterolemia as an adjunct to diet and other lipid-lowering medications.

    Categories: Compounds used in a research, industrial, or household setting, Non-statin Hypolipidemic Agents Indicated for Hyperlipidemia
  5. Target

    Small ribosomal subunit protein RACK1

    go.drugbank.com/bio_entities/BE0008967
    TargetHumans

    Required for PTK2/FAK1 phosphorylation and dephosphorylation. Regulates internalization of the muscarinic receptor CHRM2. … Scaffolding protein involved in the recruitment, assembly and/or regulation of a variety of signaling molecules. Interacts with a wide variety of proteins and plays a role in many cellular processes.

    Synonyms: Receptor for activated C kinase, Receptor for activated C kinase 1
  6. Drug

    Polyinosinic-polycytidylic acid

    go.drugbank.com/drugs/DB16467
    Investigational

    Salts: Polyinosinic polycytidylic acid sodium saltCategories: Experimental Unapproved Treatments for COVID-19, Poly I
  7. Drug

    Loxoprofen

    go.drugbank.com/drugs/DB09212
    ApprovedInvestigational

    A transdermal preparation was approved for use in Japan in January 2006. … Loxoprofen is a propionic acid derivative non-steroidal anti-inflammatory drug.

    Categories: Antiinflammatory Preparations, Non-Steroids for Topical Use, Topical Products for Joint and Muscular Pain
  8. Drug

    Helium

    go.drugbank.com/drugs/DB09155
    ApprovedInvestigationalVet approved

    It is also used as an analytical reagent in diagnostic/imaging tests to detect respiratory function of the patient. … It is a colorless, odorless, tasteless, non-toxic, inert, monatomic gas located at the top of the noble gases on the periodic table.

    Mixtures: Oxygen In Helium Mix, Oxygen In Helium Mixture
  9. Drug

    Diphenylpyraline

    go.drugbank.com/drugs/DB01146
    Approved

    Diphenylpyraline is an antihistamine. Antihistamines used in the treatment of allergy act by competing with histamine for H 1-receptor sites on effector cells. … Antihistamines prevent, but do not reverse, responses mediated by histamine alone.

    Mixtures: Eucillin "B" - Salbe, Emercreme No4 Ont EfaCategories: Antihistamines for Systemic Use
  10. Drug

    Efavirenz

    go.drugbank.com/drugs/DB00625
    ApprovedInvestigational

    For HIV infection that has not previously been treated, efavirenz and lamivudine in combination with zidovudine or tenofovir is the preferred NNRTI-based regimen. … Efavirenz is also used in combination with other antiretroviral agents as part of an expanded postexposure prophylaxis regimen to prevent HIV transmission for those exposed to materials associated with

    Mixtures: Symfi Lo, Symfi LoCategories: Antivirals used in combination for the treatment of HIV infections, Antivirals for Systemic Use