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Displaying results 171 - 180 of 2873 in total
  1. Pathway

    Bamipine H1-Antihistamine Action

    smpdb.ca/view/SMP0062882
    Drug action

    Furthermore, lowering calcium ion concentration leads to increased mast cell stability which reduces further histamine release.

    Drugs: Calcium
  2. Pathway

    Pyrrobutamine H1-Antihistamine Action

    smpdb.ca/view/SMP0062887
    Drug action

    Furthermore, lowering calcium ion concentration leads to increased mast cell stability which reduces further histamine release.

    Drugs: Calcium
  3. Pathway

    Phospholipase C Signaling Pathway

    smpdb.ca/view/SMP0063783
    Signaling

    IP3 releases calcium from the endoplasmic reticulum. PIP3 is an important regulator of AKT signaling and downstream pathways.

    Drugs: Calcium
  4. Pathway

    Muscular Gq Protien Cascade

    smpdb.ca/view/SMP0126980
    Physiological

    through calcium binding proteins and calcium-sensitive processes. … These channels are specific to calcium and only allow the passage of calcium from the ER into the cytoplasm.

    Drugs: Calcium
  5. Pathway

    Doxylamine H1-Antihistamine Immune Response Action Pathway

    smpdb.ca/view/SMP0058803
    Drug action

    Furthermore, lowering calcium ion concentration leads to increased mast cell stability which reduces further histamine release.

    Drugs: Doxylamine · Calcium
    Enzymes: Voltage-dependent P/Q-type calcium channel subunit alpha-1A, Voltage-dependent L-type calcium channel subunit beta-1
  6. Pathway

    Gabapentin Action Pathway

    smpdb.ca/view/SMP0124712
    Drug action

    The role of gabapentin is to bind to the α2δ-1 subunit of voltage-gated calcium channels, thereby inhibiting the voltage gated calcium channels. … When an action potential arrives at the nerve terminal, calcium channels are activated allowing influx of calcium ions, which stimulates the release of neurotransmitters by causing the exocytotic vesicle

    Drugs: Gabapentin · Calcium
    Enzymes: Voltage-dependent calcium channel subunit alpha-2/delta-1, Voltage-dependent N-type calcium channel subunit alpha-1B
  7. Pathway

    Dexbrompheniramine H1-Antihistamine Immune Response Action Pathway

    smpdb.ca/view/SMP0175073
    Drug action

    Furthermore, lowering calcium ion concentration leads to increased mast cell stability which reduces further histamine release.

    Drugs: Dexbrompheniramine · Calcium
    Enzymes: Voltage-dependent P/Q-type calcium channel subunit alpha-1A, Voltage-dependent L-type calcium channel subunit beta-1
  8. Pathway

    Cyproheptadine H1-Antihistamine Immune Response Action Pathway

    smpdb.ca/view/SMP0175075
    Drug action

    Furthermore, lowering calcium ion concentration leads to increased mast cell stability which reduces further histamine release.

    Drugs: Cyproheptadine · Calcium
    Enzymes: Voltage-dependent P/Q-type calcium channel subunit alpha-1A, Voltage-dependent L-type calcium channel subunit beta-1
  9. Pathway

    Promethazine H1-Antihistamine Immune Response Action Pathway

    smpdb.ca/view/SMP0175084
    Drug action

    Furthermore, lowering calcium ion concentration leads to increased mast cell stability which reduces further histamine release.

    Drugs: Promethazine · Calcium
    Enzymes: Voltage-dependent P/Q-type calcium channel subunit alpha-1A, Voltage-dependent L-type calcium channel subunit beta-1
  10. Pathway

    Chloropyramine H1-Antihistamine Immune Response Action Pathway

    smpdb.ca/view/SMP0175097
    Drug action

    Furthermore, lowering calcium ion concentration leads to increased mast cell stability which reduces further histamine release.

    Drugs: Calcium · Chloropyramine
    Enzymes: Voltage-dependent P/Q-type calcium channel subunit alpha-1A, Voltage-dependent L-type calcium channel subunit beta-1