Search

Displaying results 1 - 10 of 2873 in total
  1. Drug

    Docusate

    go.drugbank.com/drugs/DB11089
    ApprovedInvestigational

    Docusate acts by increasing the amount of water the stool absorbs in the gut, making the stool softer and easier to pass [L1801]. Docusate can be orally or rectally administered. … Still docusate is available in over-the-counter products as a common laxative.

    Synonyms: Docusate, Docusate hydrogenSalts: Docusate calcium, Docusate sodium
  2. Drug

    Calcium

    go.drugbank.com/drugs/DB01373
    ApprovedInvestigationalNutraceutical

    The best-absorbed form of calcium from a pill is a calcium salt like carbonate or phosphate. Calcium gluconate and calcium lactate are absorbed well by pregnant women. … Bone serves as an important storage point for calcium, as it contains 99% of the total body calcium. Low calcium intake may also be a risk factor in the development of osteoporosis.

    Synonyms: Calcium, Elemental calciumMixtures: Prenatal Vitamin No 53 Iron Fum Folic Acid Docusate CA DHA, Pure Calcium calcium
  3. Drug

    Calcium carbonate

    go.drugbank.com/drugs/DB06724
    ApprovedInvestigational

    Calcium carbonate may also be used as a nutritional supplement or to treat hypocalcemia. … Calcium carbonate is an inorganic salt used as an antacid. It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions.

    Synonyms: Calcium carbonate, Carbonate de calciumMixtures: PNV Ferrous Fumarate Docusate Folic Acid, Actonel With Calcium
  4. Drug

    Pantothenic acid

    go.drugbank.com/drugs/DB01783
    ApprovedInvestigationalNutraceuticalVet approved

    Pantothenic acid is the amide between pantoic acid and β-alanine and commonly found as its alcohol analog, the provitamin panthenol, and as calcium pantothenate.

    Salts: Calcium pantothenateMixtures: PNV Ferrous Fumarate Docusate Folic Acid
  5. Pathway

    Calcium carbonate Drug Metabolism

    smpdb.ca/view/SMP0130489
    Metabolic

    Calcium carbonate passes through the liver and is then excreted from the body mainly through the kidney. … Calcium carbonate is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis.

    Drugs: Calcium carbonate
  6. Pathway

    Verapamil Calcium Channel Vasodilation Action Pathway

    smpdb.ca/view/SMP0126373
    Drug action

    The inhibition of L-type calcium channels prevents the influx of calcium in vascular smooth muscle myocytes and the heart's cardiomyocytes, which prevents contraction of vascular smooth muscles and heart … Verapamil is an L-type calcium channel blocker with antiarrhythmic, antianginal, and antihypertensive activity.

    Drugs: ATP · Verapamil · Calcium · Magnesium cation
    Enzymes: Voltage-dependent L-type calcium channel subunit beta-1, Voltage-dependent calcium channel subunit alpha-2/delta-1
  7. Pathway

    Diltiazem Calcium Channel Vasodilation Action Pathway

    smpdb.ca/view/SMP0126505
    Drug action

    This effect is thought to be mediated by the voltage-dependent block of the L-type calcium channels and inhibition of calcium ion release from the ER stores, without altering the sodium-calcium coupled … transport or calcium sensitivity of myofilaments.

    Drugs: ATP · Diltiazem · Calcium · Magnesium cation
    Enzymes: Voltage-dependent L-type calcium channel subunit beta-1, Voltage-dependent calcium channel subunit alpha-2/delta-1
  8. Pathway

    Cinnarizine Calcium Channel Vasodilation Action Pathway

    smpdb.ca/view/SMP0126667
    Drug action

    Cinnarizine is an antihistamine and a calcium channel blocker. Cinnarizine inhibits contractions of vascular smooth muscle cells by blocking L-type and T-type voltage gated calcium channels. … Cinnarizine could be also viewed as a nootropic drug because of its vasorelaxating abilities (due to calcium channel blockage), which happen mostly in brain.

    Drugs: ATP · Cinnarizine · Calcium · Magnesium cation
    Enzymes: Voltage-dependent T-type calcium channel subunit alpha-1G, Voltage-dependent T-type calcium channel subunit alpha-1H
  9. Pathway

    Diltiazem Calcium Channel Cardiac Muscle Relaxation Action Pathway

    smpdb.ca/view/SMP0126292
    Drug action

    This effect is thought to be mediated by the voltage-dependent block of the L-type calcium channels and inhibition of calcium ion release from the ER stores, without altering the sodium-calcium coupled … transport or calcium sensitivity of myofilaments.

    Drugs: Diltiazem · Potassium cation · Calcium · Cyclic adenosine monophosphate
    Enzymes: Voltage-dependent P/Q-type calcium channel subunit alpha-1A, Voltage-dependent T-type calcium channel subunit alpha-1G
  10. Pathway

    Flunarizine Calcium Channel Artery Dilation Action Pathway

    smpdb.ca/view/SMP0126303
    Drug action

    Flunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. … Flunarizine inhibits the influx of extracellular calcium through myocardial and vascular membrane pores by physically plugging the channel.

    Drugs: ATP · Calcium · Magnesium cation · Flunarizine
    Enzymes: Voltage-dependent L-type calcium channel subunit beta-1, Voltage-dependent calcium channel subunit alpha-2/delta-1