Search

Displaying results 171 - 178 of 178 in total
  1. Target

    Natriuretic peptides B

    go.drugbank.com/bio_entities/BE0000979
    TargetHumans

    Involved in regulating the extracellular fluid volume and maintaining the fluid-electrolyte balance through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion (PubMed … Acts by specifically binding and stimulating NPR1 to produce cGMP, which in turn activates effector proteins that drive various biological responses (PubMed:1672777, PubMed:17349887, PubMed:17372040, PubMed

    Synonyms: Iso-ANP
  2. Target

    ADP/ATP translocase 3

    go.drugbank.com/bio_entities/BE0000624
    TargetHumans

    production and cause mitochondrial thermogenesis (By similarity). … ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell (By similarity).

    Synonyms: ANT 2, ANT 3
  3. Target

    Eph receptors

    go.drugbank.com/bio_entities/BE0028186
    TargetHumans

    Binds to EFNA3, EFNA4 and EFNA5 … Generally has an overlapping and redundant function with EPHB2.

    Synonyms: EPH- and ELK-related kinase
  4. Target

    Atrial natriuretic peptide receptor 1

    go.drugbank.com/bio_entities/BE0000556
    TargetHumans

    and subsequently PRKAA1, thereby controlling blood pressure and maintaining cardiovascular homeostasis (PubMed:36016499) … Plays an essential role in the regulation of endothelial cell senescence and vascular aging (PubMed:36016499).

    Synonyms: ANP-A
  5. Target

    Atrial natriuretic peptide receptor 2

    go.drugbank.com/bio_entities/BE0000997
    TargetHumans

    Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth

    Synonyms: ANP-B
  6. Target

    Atrial natriuretic peptide receptor 3

    go.drugbank.com/bio_entities/BE0002426
    TargetHumans

    May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. … Acts as a regulator of osteoblast differentiation and bone growth by binding to its ligand osteocrin, thereby preventing binding between NPR3/NPR-C and natriuretic peptides, leading to increase cGMP production

    Synonyms: ANP-C
  7. Target

    ADP/ATP translocase 2

    go.drugbank.com/bio_entities/BE0000709
    TargetHumans

    production and cause mitochondrial thermogenesis (By similarity). … ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell (By similarity).

    Synonyms: ANT 2
  8. Target

    ADP/ATP translocase 1

    go.drugbank.com/bio_entities/BE0000599
    TargetHumans

    production and cause mitochondrial thermogenesis (By similarity). … In addition to its ADP:ATP antiporter activity, also involved in mitochondrial uncoupling and mitochondrial permeability transition pore (mPTP) activity (PubMed:31883789).

    Synonyms: ANT 1