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Complement factor I
go.drugbank.com/bio_entities/BE0009054TargetHumansThe presence of these cofactors on healthy cells allows degradation of deposited C3b by CFI in order to prevent undesired complement activation, while in apoptotic cells or microbes, the absence of such
Polypeptides: Complement factor IDiethyltoluamide
go.drugbank.com/drugs/DB11282ApprovedDEET products are largely designed to be applied directly to human skin, where the exact mechanisms of actions in which DEET is capable of repelling insects and causing toxicity to humans is still not … Diethyltoluamide (DEET) is the common active ingredient in many insect repellent products. It is widely used to repel biting pests such as mosquitoes and ticks.
Categories: Compounds used in a research, industrial, or household settingSynonyms: 3-methyl-N,N-diethylbenzamide, N,N-diethyl-m-toluamideTitanium dioxide
go.drugbank.com/drugs/DB09536ApprovedIt is used as a pigment under the names titanium white, Pigment White 6 (PW6), or CI 77891. It is typically extracted from ilmenite, rutile and anatase. … Titanium dioxide, also known as titanium(IV) oxide or titania, is the naturally occurring oxide of titanium.
Mixtures: Alumier MD Post Procedure Prescription, Alumier MD Post Procedure Prescription Hydrocortisone FreeCategories: Compounds used in a research, industrial, or household settingBatoprazine
go.drugbank.com/drugs/DB20649ExperimentalBatoprazine is a small molecule drug. Batoprazine has a monoisotopic molecular weight of 230.11 Da.
Synonyms: 8-(1-piperazinyl)coumarinLevocarnitine
go.drugbank.com/drugs/DB00583ApprovedInvestigationalIt is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias.
Mixtures: Q 10 Suprabio +L-Carnitine, Q-GEL CARNI SOFTSULESynonyms: 3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium hydroxide, inner salt, (R)-CarnitineDNA polymerase I, thermostable
go.drugbank.com/bio_entities/BE0001665TargetThermus aquaticusIn addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity (By similarity). Unlikely to have 3'-5' exonuclease activity due to absence of a 3'-5' exonuclease domain (Probable).
Polypeptides: DNA polymerase I, thermostableType I iodothyronine deiodinase
go.drugbank.com/bio_entities/BE0009854EnzymeTargetHumansPlays a crucial role in the metabolism of thyroid hormones (TH) and has specific roles in TH activation and inactivation by deiodination (PubMed:12586771, PubMed:32718224, PubMed:18821722). Catalyzes the deiodination of L-thyroxine (T4) ...
Polypeptides: Type I iodothyronine deiodinaseSynonyms: Type-I 5'-deiodinaseMedroxyprogesterone acetate
go.drugbank.com/drugs/DB00603ApprovedInvestigational[A14848] MPA can be use to treat secondary amenorrhea, endometrial hyperplasia, abnormal uterine bleeding, osteoporosis, vasomotor symptoms in menopause, vulvar and vaginal atrophy, prevent pregnancy, … Medroxyprogesterone acetate (MPA) is a [progesterone] derivative that is more resistant to metabolism for improved pharmacokinetic properties.
Mixtures: OBAT SUNTIK KB II, DIVICONT TABLETAS 1 MG/5 MGCategories: Pregnen (4) Derivatives, P-glycoprotein inhibitorsNitrofurantoin
go.drugbank.com/drugs/DB00698ApprovedInvestigationalVet approved[L6856,L6859,L6862] Nitrofurantoin is converted by bacterial nitroreductases to electrophilic intermediates which inhibit the citric acid cycle as well as synthesis of DNA, RNA, and protein. … [A179824] This drug is more resistant to the development of bacterial resistance because it acts on many targets at once.
Categories: P-glycoprotein substrates, Heterocyclic Compounds, 1-RingSynonyms: N-(5-Nitrofurfurylidene)-1-aminohydantoin, 1-((5-nitro-2-furanyl)methylene)amino-2,4-imidazolidenedioneValerian
go.drugbank.com/drugs/DB13196ApprovedValerian is extracted from a herb that is a perennial flowering plant. Valerian root is reported to have sedative and anxiolytic effects however its mechanism of action is not completely understood. … Valerian is a food ingredient permitted for direct addition to food for human consumption as a natural flavoring substance.
Mixtures: Bio-strath No. 8 Gouttes, Herbal Slumber CapCategories: Cytochrome P-450 CYP2C19 Inducers, Cytochrome P-450 CYP3A Inducers