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Displaying results 171 - 180 of 13019 in total
  1. Drug

    Vincristine

    go.drugbank.com/drugs/DB00541
    ApprovedInvestigational

    because of lack of significant bone–marrow suppression (at recommended doses) and of unique clinical toxicity (neuropathy). … Vincristine is indicated for the treatment of acute leukaemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, and acute panmyelosis. vincristine sulfate is often chosen as part of polychemotherapy

    Products: CYTOCRISTIN AQUEOUS (VL OF 1ML), CITOMID RU ® SOLUCION INYECTABLE
  2. Drug

    VidPrevtyn Beta

    go.drugbank.com/drugs/DB16427
    Approved

    Sf9 cells of the fall armyworm, _Spodoptera frugiperda_ - combined with GSK's AS03 adjuvant. … [L49691] It comprises a recombinant SARS-CoV-2 spike protein (B.1.351 strain) - produced by recombinant DNA technology using a baculovirus expression system in an insect cell line that is derived from

    Synonyms: SARS-CoV-2 prefusion Spike delta TM protein, recombinant (B.1.351 strain)
  3. Drug

    Raxtozinameran

    go.drugbank.com/drugs/DB18228
    ApprovedInvestigational

    It works by binding to the spike (S) protein of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), which is a transmembrane glycoprotein that plays a vital role in viral pathogenesis, evolutions … [A273680] Raxtozinameran was first approved by the FDA and EMA through emergency use in December 2020.[L52565,L39272]

    Synonyms: messenger RNA (mRNA), 5'-capped, encoding a full-length, codon-optimised pre-fusion stabilised conformation variant (K982P and V983P) of the SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), RNA (recombinant 5′-[1,2-[(3′-O-methyl)m7G-(5′→5′)-ppp-Am]]-capped all uridine→N1-methylpseudouridine-substituted severe acute respiratory syndrome coronavirus 2 spike glycoprotein secretory signal peptideProducts: COMIRNATY® VACUNA DE ARNM CONTRA COVID-19
  4. Drug

    Fexofenadine

    go.drugbank.com/drugs/DB00950
    ApprovedInvestigational

    Fexofenadine is an over-the-counter second-generation antihistamine used in the treatment of various allergic symptoms. … [A1452] Fexofenadine is the major active metabolite of [terfenadine][A1495] and is administered as a racemic mixture in which both enantiomers display approximately equivalent antihistamine activity.

    Mixtures: Allegra D-12 Hour, Allegra-DCategories: Histamine H1 Antagonists, Non-Sedating
  5. Drug

    Urofollitropin

    go.drugbank.com/drugs/DB00094
    ApprovedVet approvedWithdrawn

    It consists of two non-covalently linked, non-identical glycoproteins designated as the alpha- and beta- subunits. The alpha- and beta- subunits have 92 and 111 amino acids. … Urofollitropin may also be used to cause the ovary to produce several follicles, which can then be harvested for use in gamete intrafallopian transfer (GIFT) or in vitro fertilization (IVF).

    Categories: Sex Hormones and Modulators of the Genital SystemProducts: Sanzyme FSH 75 IU (Urofollitropin Lyophilised Powder for Solution for Injection BP, 75 IU/vial) & Sodium Chloride Injection USP 1ml Ampoule (Sterile 0.9% w/v solution of Sodium Chloride), Sanzyme FSH 150 IU (Urofollitropin Lyophilised Powder for Solution for Injection BP, 150 IU/vial) & Sodium Chloride Injection USP 1ml Ampoule (Sterile 0.9% w/v solution of Sodium Chloride)
  6. Drug

    Plant-based virus-like particles, recombinant, adjuvanted COVID-19 vaccine

    go.drugbank.com/drugs/DB16757
    Approved

    [L40694] It is composed of VLPs expressing SARS-CoV-2 spike protein trimers (stabilized in a pre-fusion conformation) and is mixed with the AS03 adjuvant system prior to administration. … for the prevention of COVID-19.

    Synonyms: Recombinant SARS-CoV-2 spike (S)-protein virus-like particle
  7. Drug

    Benzyl alcohol

    go.drugbank.com/drugs/DB06770
    ApprovedInvestigational

    Mixtures: Fast Freeze Lidocaine Roll-On, ZOLBENE CREMA TOPICA (CALAMINA 5% + OXIDO DE ZINC 5% + ALCOHOL BENCILICO 1%)Products: Babys Own Teething Gel, Baby's Own Teething Gel 2.5%
  8. Drug

    BCG vaccine

    go.drugbank.com/drugs/DB12768
    ApprovedInvestigationalWithdrawn

    BCG vaccine has been investigated for the treatment of Neoplasms, Bladder Cancer, Neoplasms by Site, Urologic Diseases, and Urologic Neoplasms, among others.

    Products: SII-ONCO-BCG (Powder for Intravesical Instillation) BCG Live USP. 1 vial of 40 mg/ml
  9. Drug

    Castor oil

    go.drugbank.com/drugs/DB11113
    ApprovedNutraceuticalVet approved

    Due to its renewability and high versatility in addition to being the only commercial source of a hydroxylated fatty acid [A31170], castor oil has been used as a vital raw material for the chemical industry … Castor oil is a rich source of [DB02955], which represents up to 90% of the total castor oil content.

    Products: OLIO DI RICINO, Huile De Ricin
  10. Drug

    Potassium chloride

    go.drugbank.com/drugs/DB00761
    ApprovedInvestigationalWithdrawn

    A white crystal or crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia, in buffer solutions, and in fertilizers and explosives. … The FDA withdrew its approval for the use of all solid oral dosage form drug products containing potassium chloride that supply 100 mg or more of potassium per dosage unit, except for controlled-release

    Mixtures: OQ-BALANS, OQ-BALANSSynonyms: Chloride of potash, Muriate of potash