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Mometasone furoate
go.drugbank.com/drugs/DB14512ApprovedInvestigationalVet approvedMometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and certain skin conditions[FDA Label] . It has a glucocorticoid receptor binding affinity 22 times stronger than dexamethasone and highe...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersProducts: MOMETASONFUROAT 1A PH 50UG, MOMETASONFUROAT AL 50UG/SPChlorhexidine
go.drugbank.com/drugs/DB00878ApprovedInvestigationalVet approvedWithdrawnChlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental practice for the treatment of inflammatory dental conditions caused by microorganisms. It is one of the most common skin and mucous memb...
Mixtures: KLOROBEN FORT 3 MG/ML+ 2 MG/ML GARGARA, 200 ML, KLOROBEN 1,5 MG/ML + 1,2 MG/ML GARGARA, 200 MLSynonyms: 1,1'-Hexamethylene bis(5-(p-chlorophenyl)biguanide)Allantoin
go.drugbank.com/drugs/DB11100ApprovedInvestigationalIn healthy human volunteers, the mean plasma concentration of allantoin is about 2-3 mg/l.
Mixtures: Renuu NL, SL Mineral TonerProducts: Dr Young 2p Blemish Base SPF35 PA, Young 2P Pearl Brightening Balm SPF35 PAInsulin glargine
go.drugbank.com/drugs/DB00047ApprovedInvestigationalThe resulting protein is soluble at pH 4 and forms microprecipitates at physiological pH 7.4 allowing for the slow release of small amounts of insulin glargine, giving the drug a long duration of action … As of 2015, insulin glargine was reformulated by Sanofi as the product Toujeo in an extra-concentrated form containing 300IU/mL (compared to 100IU/mL contained in Lantus).
Mixtures: Soliqua SoloStar 100units/mL+33mcg/mL solution for injection in a pre-filled pen, Soliqua SoloStar 100units/mL+50mcg/mL solution for injection in a pre-filled penCategories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Enzyme InducersUbidecarenone
go.drugbank.com/drugs/DB09270ApprovedInvestigationalNutraceuticalUbidecarenone, also called coenzyme Q10, is a 1,4-benzoquinone. From its name (Q10), the Q refers to the constitutive quinone group, and 10 is related to the number of isoprenyl subunits in its tail. It is a powerful antioxidant, a lipid...
Mixtures: Q 10 Suprabio +L-CarnitineCategories: P-glycoprotein substratesSiltuximab
go.drugbank.com/drugs/DB09036ApprovedInvestigationalSiltuximab prevents the binding of IL-6 to soluble and membrane-bound IL-6 receptors by forming high affinity complexes with human interleukin-6 (IL-6). … MCD is a rare blood disorder caused by dysregulated IL-6 production, proliferation of lymphocytes, and subsequent enlargement of the lymph nodes.
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersPembrolizumab
go.drugbank.com/drugs/DB09037ApprovedInvestigationalPembrolizumab is a highly selective IgG4-kappa humanized monoclonal antibody against PD-1 receptors. … It was generated by grafting the variable sequences of a very high-affinity mouse antihuman PD-1 antibody onto a human IgG4-kappa isotype containing a stabilizing S228P Fc mutation.
Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitors, PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitorsProducts: KEYTRUDA SOLUTION FOR INFUSION 25MG/ML, KEYTRUDA 100 MG/4 ML IV INFUZYONLUK COZELTI İÇEREN FLAKON, 1 ADETNicotinamide
go.drugbank.com/drugs/DB02701ApprovedInvestigationalAn important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent n...
Mixtures: Diapia Adl Ever-curecream, Diapia Adl Ever-cure SerumCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 InhibitorsPropofol
go.drugbank.com/drugs/DB00818ApprovedInvestigationalVet approvedPropofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medic...
Categories: P-glycoprotein inducers, Cytochrome P-450 SubstratesProducts: FOPROL, PROPOFOL-PF %1 200 MG/20 ML I.V. ENJEKSİYONLUK/İNFÜZYONLUK EMÜLSİYON, 5 ADETMetoclopramide
go.drugbank.com/drugs/DB01233ApprovedInvestigationalDiabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative impact on quality of life and poses a significant burden on the healthcare system. Metoclopramide is a dopamine antagonist used to treat...
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: PP-METOCLOPRAMIDE TABLET, TOPRAM