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Clodronic acid
go.drugbank.com/drugs/DB00720ApprovedInvestigationalVet approved[A203111] Clodronic acid is not FDA approved, but is approved in Canada.[L13910] … Clodronic acid is a first generation bisphosphonate similar to [etidronic acid] and [tiludronic acid].
Categories: Drugs Affecting Bone Structure and MineralizationProducts: Ostac Cap 400mgHydroxide ion
go.drugbank.com/drugs/DB14522InvestigationalMixtures: OHTrust Nano Ion WaterSynonyms: Hydroxide ionXylometazoline
go.drugbank.com/drugs/DB06694ApprovedXylometazoline is an imidazoline derivative [A228523] with sympathomimetic and nasal decongestant activity. … Xylometazoline works by binding to alpha (α)-adrenergic receptors to cause vasoconstriction of nasal blood vessels.
Categories: Decongestants and AntiallergicsProducts: Cold and Allergy Decongestant Nasal Spray, Otrivin Cold and Allergy Decongestant Nose DropsPuberty, Delayed
go.drugbank.com/conditions/DBCOND0001010Synonyms: Delay in sexual development AND/OR puberty (finding), Delay in sexual development and puberty, NEC -RETIRED-Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3
go.drugbank.com/bio_entities/BE0002195TargetEnzymeHumansCatalyzes hydroxylation and glycosylation of Lys residues in the MBL1 collagen-like domain, giving rise to hydroxylysine and 1,2-glucosylgalactosyl-5-hydroxylysine residues (PubMed:25419660). … Plays a redundant role in catalyzing the formation of hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens (PubMed:11956192, PubMed:12475640, PubMed:18298658, PubMed:18834968, PubMed:30089812
Polypeptides: Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3Disintegrin and metalloproteinase domain-containing protein 9
go.drugbank.com/bio_entities/BE0003412TargetHumansMetalloprotease that cleaves and releases a number of molecules with important roles in tumorigenesis and angiogenesis, such as TEK, KDR, EPHB4, CD40, VCAM1 and CDH5. … May mediate cell-cell, cell-matrix interactions and regulate the motility of cells via interactions with integrins
Polypeptides: Disintegrin and metalloproteinase domain-containing protein 9Sodium- and chloride-dependent GABA transporter 3
go.drugbank.com/bio_entities/BE0004733TargetHumansCan also mediate transport of beta-alanine and to a lower extent that of taurine and hypotaurine (By similarity) … Mediates sodium- and chloride-dependent transport of gamma-aminobutyric acid (GABA) (PubMed:7874447).
Polypeptides: Sodium- and chloride-dependent GABA transporter 3Disintegrin and metalloproteinase domain-containing protein 33
go.drugbank.com/bio_entities/BE0019245TargetHumansPromotes and maintains a proliferative phenotype in vascular smooth muscle cells through regulation of the PI3K/AKT and ERK signaling pathways (PubMed:33982767). … Metalloprotease that cleaves and sheds the ectodomains of cell-surface proteins and thereby contributes to angiogenesis, cell differentiation, inflammation, and cell proliferation (PubMed:14676211, PubMed
Polypeptides: Disintegrin and metalloproteinase domain-containing protein 33Aminosalicylic acid
go.drugbank.com/drugs/DB00233ApprovedInvestigationalAn antitubercular agent often administered in association with isoniazid. The sodium salt of the drug is better tolerated than the free acid.
Categories: Aminosalicylic Acid and DerivativesProducts: Nemasol Sodium Tab 500mgAmrinone
go.drugbank.com/drugs/DB01427ApprovedWithdrawnAmrinone (or inamrinone) is a type 3 pyridine phosphodiesterase inhibitor. It is used in the treatment of congestive heart failure.
Categories: Calcium-Regulating Hormones and Agents, Compounds used in a research, industrial, or household settingProducts: Inocor Liq 5mg/ml