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Displaying results 1791 - 1800 of 10000 in total
  1. Drug

    Prasugrel

    go.drugbank.com/drugs/DB06209
    ApprovedInvestigational

    FDA approved in 2009. … Prasugrel, a thienopyridine derivative, is a platelet activation and aggregation inhibitor structurally and pharmacologically related to clopidogrel and ticlopidine.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 SubstratesProducts: PRASUGREL AL 5MG HBR FTA, PRASUGREL AL 10MG HBR FTA
  2. Drug

    Coagulation Factor IX (Recombinant)

    go.drugbank.com/drugs/DB00100
    Approved

    medium that is then processed and purified for use as a pharmaceutical agent. … Recombinant Coagulation Factor IX is a purified Factor IX glycoprotein produced by recombinant DNA technology.

    Products: OCTANINE F ® 1000 UI, OCTANINE® F 500 UI
  3. Drug

    Diphenoxylate

    go.drugbank.com/drugs/DB01081
    ApprovedIllicitInvestigational

    When diphenoxylate is used alone, it is classified as a Schedule II. … A meperidine congener used as an antidiarrheal, usually in combination with atropine. At high doses, it acts like morphine.

    Mixtures: PHARMANIAGA DIPHENOXYLATE A TABLET, LOMOTİL 2,5 MG + 0,025 MG / 5 ML ORAL ÇÖZELTİ, 60 MLCategories: Heterocyclic Compounds, 1-Ring
  4. Drug

    Isavuconazonium

    go.drugbank.com/drugs/DB06636
    ApprovedInvestigational

    Isovuconazonium has excellent oral bioavailability, predictable pharmacokinetics, and a good safety profile, making it a reasonable alternative to its few other competitors on the market. … Isavuconazonium is a second-generation triazole antifungal approved on March 6, 2015 by the FDA and July 2015 by the EMA for the treatment of adults with invasive aspergillosis and invasive mucormycosis

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP2B6 InducersProducts: CRESEMBA® 200 MG POLVO LIOFILIZADO ESTERIL PARA RECONSTITUIR, CRESEMBA ® CAPSULAS
  5. Drug

    Caspofungin

    go.drugbank.com/drugs/DB00520
    ApprovedInvestigational

    Caspofungin (brand name Cancidas worldwide) is an antifungal drug and the first member of a new drug class called the echinocandins, as coined by Merck & Co., Inc. … It shows activity against infections with Aspergillus and Candida, and works by inhibiting β(1,3)-D-Glucan of the fungal cell wall.

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP3A InhibitorsSynonyms: (4R,5S)-5-((2-Aminoethyl)amino)-N(sup 2)-(10,12-dimethyltetradecanoyl)-4-hydroxy-L-ornithyl-L-threonyl-trans-4-hydroxy-L-prolyl-(S)-4-hydroxy-4-(p-hydroxyphenyl)-L-threonyl-threo-3-hydroxy-L-ornithyl-trans, -3-hydroxy-L-proline cyclic (6-1)-peptide
  6. Drug

    Phleum pratense pollen

    go.drugbank.com/drugs/DB10394
    ApprovedInvestigational

    Phleum pratense pollen allergenic extract is used in allergenic testing.

    Mixtures: SLITone ULTRA D. glomerata/ L. perenne/ P. pratense/ P. pratensis/ A. odoratum, Oralair 100 IRProducts: GRAZAX 75.000 SQ-T ORAL LIYOFILIZAT 100 TABLET, Standardized Grass Pollen - Timothy (100 Bau/ml)
  7. Drug

    Methyl aminolevulinate

    go.drugbank.com/drugs/DB00992
    ApprovedInvestigational

    Methyl aminolevulinate is a prodrug that is metabolised to Protoporphyrin IX (a photosensitizer) used in photodynamic therapy.

    Synonyms: methyl 5-aminolevulinate, methyl δ-aminolevulinateProducts: METVIX® CREMA 160 MG/G, Luxerm 160 mg/g Creme
  8. Drug

    Clomipramine

    go.drugbank.com/drugs/DB01242
    ApprovedInvestigationalVet approved

    See toxicity section below for a complete listing of side effects. … Clomipramine, the 3-chloro analog of imipramine, is a dibenzazepine-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines.

    Categories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic IndexSynonyms: 3-(3-chloro-5H-dibenzo[b,F]azepin-5-yl)-N,N-dimethylpropan-1-amine, 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethyl-1-propanamine
  9. Drug

    Protamine

    go.drugbank.com/drugs/DB13700
    ApprovedInvestigationalWithdrawn

    Products: PROTAMYN 1000® UI/ML AMPOLLA, Protamin Meda 1000 I.E./ml - Injektionslösung
  10. Drug

    Ornidazole

    go.drugbank.com/drugs/DB13026
    Investigational

    Ornidazole has been used in trials studying the prevention of Elective Colorectal Surgery.

    Mixtures: ORNISASIN 500 MG/500 MG FILM TABLET, 10 ADET, ORNISASIN 500 MG/500 MG FILM TABLET, 20 ADETCategories: Heterocyclic Compounds, 1-Ring