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Betaine
go.drugbank.com/drugs/DB06756ApprovedInvestigationalNutraceuticalThe FDA and EMA have approved the product Cystadane (betaine anhydrous, oral solution) for the treatment of homocystinuria,[L43105,L43115] and the EMA has approved the use of Amversio (betaine anhydrous … Currently, no treatments are available to correct the genetic causes of homocystinuria.
Aluminum chloride
go.drugbank.com/drugs/DB11081ApprovedInvestigationalAluminum chloride is a chemical compound with the chemical formula AlCl3. When contaminated with iron chloride, it often displays a yellow color compared to the white pure compound. … In antiperspirant products, FDA approves the use of aluminum chloride as an active ingredient up to 15%, calculated on the hexahydrate form, in an aqueous solution nonaerosol dosage form [L2012].
Poloxamer 188
go.drugbank.com/drugs/DB11333ApprovedP188 was originally approved by the FDA in the 1960s as a therapeutic agent to reduce viscosity in the blood before transfusions, however it is no longer available in any approved products [A27217]. … There is an evidence of P188 increasing the structural stability and resealing of the plasma membrane via direct incorporation into the phospholipid bilayer [A27217].
Nitrous acid
go.drugbank.com/drugs/DB09112ApprovedInvestigationalIt is on the World Health Organization's List of Essential Medicines, a list of the most important medications needed in a basic health system. … Nitrous acid (as sodium nitrite) is used as part of an intravenous mixture with sodium thiosulfate to treat cyanide poisoning.
Verteporfin
go.drugbank.com/drugs/DB00460ApprovedInvestigationaloxygen and other reactive oxygen radicals, resulting in local damage to the endothelium and blockage of the vessels. … It is used as a photosensitizer in photodynamic therapy to eliminate abnormal blood vessels in wet form macular degeneration.
Irbesartan
go.drugbank.com/drugs/DB01029ApprovedInvestigationalIrbesartan is an angiotensin receptor blocker (ARB) indicated to treat hypertension or diabetic nephropathy. … [L7456,L7459] It can also be used as part of a combination product with [hydrochlorothiazide] for patients not well controlled or not expected to be well controlled on monotherapy.
Mixtures: IRBESARTAN E IDROCLOROTIAZIDE EG, IRBESARTAN E IDROCLOROTIAZIDE EGCategories: Agents Acting on the Renin-Angiotensin System, Angiotensin 2 Receptor BlockerPotassium citrate
go.drugbank.com/drugs/DB09125ApprovedInvestigationalVet approvedIn the monohydrate form it is highly hygroscopic and deliquescent. Potassium citrate is used to treat a kidney stone condition called renal tubular acidosis. … Potassium Citrate is indicated also for the management of Hypocitraturic calcium oxalate nephrolithiasis.
Mixtures: Cal-mag (one To One) With Potass & ZincProducts: UROCIT-K® 10 MEQ TABLETAS DE LIBERACION PROLONGADAChloroprocaine
go.drugbank.com/drugs/DB01161ApprovedInvestigationalSimilar to other local anesthetics, it increases the threshold for electrical excitation in nerves by slowing the propagation of the nerve impulse and reducing the rate of rise of the action potential. … [L43402] The pharmacological profile of chloroprocaine is characterized by a short latency and duration, similar to the one observed with [lidocaine].
International brands: Nesacaine-CEProducts: Nesacaine Ce 2% Inj 20mg/ml, Nesacaine Ce 3% Inj 30mg/mlHomatropine methylbromide
go.drugbank.com/drugs/DB00725ApprovedHomatropine methylbromide is a quaternary ammonium muscarinic acetylcholine receptor antagonist belonging to the group of medicines called anti-muscarinics. … It may also be used to prevent nausea, vomiting, and motion sickness.
Synonyms: Metilbromuro de homatropinaDextrothyroxine
go.drugbank.com/drugs/DB00509ApprovedWithdrawnThe major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (monoiodotyrosine) and the coupling of iodotyrosines (diiodotyrosine) in the thyroglobulin. … Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood.