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Rickettsia Infections
go.drugbank.com/conditions/DBCOND0035121Synonyms: Disease due to Genus RickettsiaTrimetazidine
go.drugbank.com/drugs/DB09069ApprovedInvestigationalTrimetazidine is a piperazine derivative indicated for the symptomatic treatment of stable angina pectoris in patients inadequately controlled or intolerant to first line therapies. … [A233255,A233260] Acidic conditions, caused by anaerobic metabolism and fatty acid oxidation, in response to myocardial ischemia, activate sodium-hydrogen and sodium-calcium antiport systems.
Osilodrostat
go.drugbank.com/drugs/DB11837ApprovedInvestigational[L12123] It has undergone phase II clinical trials for the treatment of solid tumours, hypertension, and heart failure, but development for these indications was discontinued by Novartis in January 2013 … Cushing's disease),[A191850] and was granted FDA approval and Orphan Drug designation in the US in March 2020 for the same indication.[L12162]
Carbenicillin
go.drugbank.com/drugs/DB00578ApprovedIt is susceptible to gastric juice and penicillinase and may damage platelet function.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseRiboflavin
go.drugbank.com/drugs/DB00140ApprovedInvestigationalNutraceuticalVet approvedIt occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms in tissues and cells are as flavin mononucleotide and flavin-adenine dinucleotide.
Mixtures: New Chapter's D'adamo 4 Your Type Multiple for Type O, For-2Medium-chain triglycerides
go.drugbank.com/drugs/DB13959ApprovedInvestigationalIn the body, MCTs are broken down into glycerol and free fatty acids, which are directly absorbed into the blood stream and transported to the target organs to exert a range of biological and metabolic … Medium-chain triglycerides (MCTs) are triglycerides made up of a glycerol backbone and three fatty acids with an aliphatic tail of six to 12 carbon atoms.
Mixtures: OMEGA PLUS EMULSION FOR INFUSION, SmofKabiven Emulsion for InfusionCategories: Solutions for Parenteral NutritionCholine salicylate
go.drugbank.com/drugs/DB14006ApprovedNutraceuticalCholine Salicylate is the choline salt of salicylic acid, used as an analgesic, antipyretic and antirheumatic. It relieves mild to moderate pain and reduce fever and inflammation or swelling. … It is used to treat arthritis in both children and adults. This medicine can also be used for fever [L2129].
Lefamulin
go.drugbank.com/drugs/DB12825ApprovedLefamulin is a pleuromutilin antibiotic used for the treatment of bacterial community-acquired pneumonia. … [L8093] This drug is the first semi-synthetic pleuromutilin that has been designed for systemic administration.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseMethyldopa
go.drugbank.com/drugs/DB00968ApprovedInvestigational[A231784] It is an analog of DOPA (3,4‐hydroxyphenylanine), and it is a prodrug, meaning that the drug requires biotransformation to an active metabolite for therapeutic effects. … [A1499] Methyldopa exists in two isomers D-α-methyldopa and L-α-methyldopa, which is the active form.
Categories: Antihypertensive Agents Indicated for HypertensionArbutin
go.drugbank.com/drugs/DB11217ApprovedArbutin was shown to be less cytotoxic to melanocytes in culture compared to [DB09526] [A32942]. … It has also been used as an anti-infective for the urinary system as well as a diuretic [F43].
Synonyms: hydroquinone O-β-D-glucopyranoside, Hydroquinone-O-beta-D-glucopyranosideMixtures: OHUI White Extreme Illuminating Pact No.10, OHUI White Extreme Illuminating Pact No.10