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Displaying results 1811 - 1820 of 10000 in total
  1. Indication

    Polyneuropathies

    go.drugbank.com/conditions/DBCOND0030109
    Drugs: Vutrisiran
    Synonyms: Other neurologic disorders in Lyme disease
  2. Drug

    Velmupressin

    go.drugbank.com/drugs/DB18783
    Investigational

    Synonyms: L-prolinamide, 4-chloro-n-(4-mercapto-1-oxobutyl)-l-phenylalanyl-3-(2-thienyl)-l-alanyl-l-valyl-l-asparaginyl-l-cysteinyl-n-(4-((aminoiminomethyl)amino)butyl)-, cyclic (1->5)-thioether
  3. Indication

    Elevation of serum triglyceride levels

    go.drugbank.com/conditions/DBCOND0097366
    Drugs: Atorvastatin · Lovastatin · Pitavastatin · Pravastatin
    Synonyms: Increases in triglycerides, Increase in blood triglycerides
  4. Target

    Atrial natriuretic peptide receptor 1

    go.drugbank.com/bio_entities/BE0000556
    TargetHumans

    Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis (PubMed:39543315). … Plays an essential role in the regulation of endothelial cell senescence and vascular aging (PubMed:36016499).

    Synonyms: ANP-A, ANPR-A
  5. Target

    Interferon-inducible protein AIM2

    go.drugbank.com/bio_entities/BE0011287
    TargetHumans

    Also acts as a regulator of neurodevelopment via its role in the DNA damage response: acts by promoting neural cell death in response to DNA damage in the developing brain, thereby purging genetically … Also acts as a mediator of pyroptosis, necroptosis and apoptosis (PANoptosis), an integral part of host defense against pathogens, in response to bacterial infection (By similarity).

    Synonyms: Absent in melanoma 2
  6. Drug

    Ioversol

    go.drugbank.com/drugs/DB09134
    ApprovedInvestigational

    Ioversol is a non-ionic compound with a tri-iodinated benzene ring used as a contrast dye in diagnostic procedures to visualize different types of organs and tissues. … [L41780] Iodine has a high atomic density, which gives it the ability to attenuate X-rays.

    Categories: Compounds used in a research, industrial, or household setting, X-Ray Contrast ActivitySynonyms: N,N'-Bis (2,3-dihydroxypropyl)-5-[N-(2-hydroxyethyl) -glycolamido] -2,4,6-triiodoisophthalamide
  7. Drug

    Tetracycline

    go.drugbank.com/drugs/DB00759
    ApprovedInvestigationalVet approvedWithdrawn

    The FDA withdrew its approval for the use of all liquid oral drug products formulated for pediatric use containing tetracycline in a concentration greater than 25 mg/ml. … Tetracycline is a broad spectrum polyketide antibiotic produced by the Streptomyces genus of Actinobacteria.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsSynonyms: (4S,4aS,5aS,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide
  8. Indication

    Polyneuritis

    go.drugbank.com/conditions/DBCOND0096968
    Drugs: Cocarboxylase
    Synonyms: Other neurologic disorders in Lyme disease
  9. Target

    Serine/threonine-protein kinase Nek9

    go.drugbank.com/bio_entities/BE0009500
    TargetHumans

    Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation (PubMed:12101123, PubMed:12840024, PubMed:14660563, PubMed:19941817).

    Synonyms: Never in mitosis A-related kinase 9
  10. Drug

    2-[3-(5-Mercapto-[1,3,4]thiadiazol-2yl)-ureido]-N-methyl-3-pentafluorophenyl-propionamide

    go.drugbank.com/drugs/DB07988
    Experimental

    Categories: Heterocyclic Compounds, 1-Ring