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Diffuse Large B-Cell Lymphoma (DLBCL)
go.drugbank.com/conditions/DBCOND0028221Synonyms: Malignant lymphoma, large B-cell, diffuse, no International Classification of Diseases for Oncology subtype, Malignant lymphoma, large B-cell, diffuse, no ICD-O subtypeDonepezil
go.drugbank.com/drugs/DB00843ApprovedInvestigationalDonepezil was first approved by the FDA in 1996, and its extended-release form was approved in combination with [Memantine] in 2014 to manage moderate and severe forms of Alzheimer's dementia. … [L7916,L7937] A donepezil transdermal delivery system, Adlarity, was approved by the FDA in March 2022 for the treatment of Alzheimer's dementia.
International brands: Nomi-NoxProducts: Nb-donepezil, DONEPEZIL WIN MEDICALenacapavir
go.drugbank.com/drugs/DB15673ApprovedInvestigational[A244170, A244175] Lenacapavir is a first-in-class capsid inhibitor that demonstrates picomolar HIV-1 inhibition as a monotherapy _in vitro_, little to no cross-resistance with existing antiretroviral … HIV/AIDS remains an area of concern despite the introduction of numerous successful therapies, mainly due to the emergence of multidrug resistance and patient difficulty in adhering to treatment regimens
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseSynonyms: N-((1S)-1-(3-(4-CHLORO-3-(METHANESULFONAMIDO)-1-(2,2,2-TRIFLUOROETHYL)-1H-INDAZOL-7-YL)-6-(3-(METHANESULFONYL)-3-METHYLBUT-1-YN-1-YL)PYRIDIN-2-YL)-2-(3,5- DIFLUOROPHENYL)ETHYL)-2-((3BS,4AR)-5,5-DIFLUORO, 1H-CYCLOPROPA(3,4)CYCLOPENTA(1,2-C)PYRAZOLE, N-((1S)-1-(3-(4-CHLORO-3-((METHYLSULFONYL)AMINO)-1-(2,2,2-TRIFLUOROETHYL)-1H-INDAZOL-7-YL)-6-(3-METHYL-3-(METHYLSULFONYL)-1-BUTYN-1-YL)-2-PYRIDINYL)-2-(3,5-Idebenone
go.drugbank.com/drugs/DB09081ApprovedInvestigationalLack of improvement in cognitive function halted its production for these conditions, however it continues to be investigated for use in other conditions associated with mitochondrial damage. … It is not currently approved for use by either the Food and Drug Administration (USA) or Health Canada.
Categories: Compounds used in a research, industrial, or household setting, Psychostimulants, Agents Used for ADHD and NootropicsBictegravir
go.drugbank.com/drugs/DB11799ApprovedInvestigationalIt has been approved for HIV-1 monotherapy combined with 2 other antiretrovirals in a single tablet.[L43677] … Bictegravir is a recently approved investigational drug that has been used in trials studying the treatment of HIV-1 and HIV-2 infection.
Categories: Antivirals used in combination for the treatment of HIV infections, Antivirals for Systemic UseHydroxide ion
go.drugbank.com/drugs/DB14522InvestigationalMixtures: OHTrust Nano Ion WaterSynonyms: Hydroxide ionDiethyltoluamide
go.drugbank.com/drugs/DB11282ApprovedDEET products are largely designed to be applied directly to human skin, where the exact mechanisms of actions in which DEET is capable of repelling insects and causing toxicity to humans is still not … Diethyltoluamide (DEET) is the common active ingredient in many insect repellent products. It is widely used to repel biting pests such as mosquitoes and ticks.
Categories: Compounds used in a research, industrial, or household settingSynonyms: 3-methyl-N,N-diethylbenzamide, N,N-diethyl-m-toluamideAtorvastatin
go.drugbank.com/drugs/DB01076ApprovedInvestigationalPrescribing statins is considered standard practice for patients following any cardiovascular event, and for people who are at moderate to high risk of developing cardiovascular disease. … [A181084] An elevated cholesterol level (elevated low-density lipoprotein (LDL) levels in particular) is a significant risk factor for the development of CVD.
Categories: Hypolipidemic Agents Indicated for HyperlipidemiaProducts: Nb-atorvastatin, Rbx-atorvastatinForeskin keratinocyte (neonatal)
go.drugbank.com/drugs/DB10772ApprovedIn 1981, O’Conner and his group utilized cultured autologous epithelium to coat burn defects for the first time. … It is used for grafting onto partial-thickness wounds, where it offers a favorable matrix for host cell migration [L2452].