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Displaying results 1831 - 1840 of 10000 in total
  1. Drug

    Interferon alfa

    go.drugbank.com/drugs/DB05258
    ApprovedInvestigationalWithdrawn

    Interferon alfa contains several naturally occurring IFN-α subtypes and is purified by affinity chromatography. … Multiferon consists of the 6 major subtypes are IFN-α1, IFN-α2, IFN-α8, IFN-α10, IFN-α14 and IFN-α21. Of these, IFN-α2 and IFN-α14 are glycosylated.

    Synonyms: IFN-α, HuIFN-alpha-LeCategories: Interferon Type I, Cytochrome P-450 CYP1A2 Inhibitors
  2. Drug

    Methyl aminolevulinate

    go.drugbank.com/drugs/DB00992
    ApprovedInvestigational

    Methyl aminolevulinate is a prodrug that is metabolised to Protoporphyrin IX (a photosensitizer) used in photodynamic therapy.

    Synonyms: methyl 5-aminolevulinate, methyl δ-aminolevulinateProducts: METVIX® CREMA 160 MG/G, Luxerm 160 mg/g Creme
  3. Drug

    Ensulizole

    go.drugbank.com/drugs/DB11115
    Approved

    Ensulizole, also known as 2-phenylbenzimidazole-5-sulfonic acid, is a water-soluble sunscreen agent that absorbs strongly at UV-B wavelengths. … It was demonstrated by studies that ensulizole treatment provided protection against cyclobutane pyrimidine dimers and photosensitized the formation of oxidized guanine bases after UV-A or UV-B exposure

    Mixtures: Aqua Fusion SPF 15 Peau Normale A Seche, Happyderm SPF 15 Peaux Normales A SechesCategories: Heterocyclic Compounds, 2-Ring
  4. Drug

    Phenylbutazone

    go.drugbank.com/drugs/DB00812
    ApprovedVet approvedWithdrawn

    A drug that has anti-inflammatory, antipyretic, and analgesic activities. It is especially effective in the treatment of ankylosing spondylitis. … It also is useful in rheumatoid arthritis and Reiter's syndrome (investigational indication).

    Synonyms: 3,5-Dioxo-1,2-diphenyl-4-n-butylpyrazolidine, 4-n-Butyl-1,2-diphenyl-3,5-pyrazolidinedioneCategories: Non COX-2 selective NSAIDS, Cytochrome P-450 Substrates
  5. Drug

    Trastuzumab deruxtecan

    go.drugbank.com/drugs/DB14962
    ApprovedInvestigational

    Trastuzumab deruxtecan is a HER2-directed antibody attached to a topoisomerase inhibitor that is approved for use in certain types of treatment-resistant HER2-positive cancers. … [L10842] It is classified as an antibody-drug conjugate. The cleavable peptide linker used to bind the antibody and drug in this product distinguishes it from other members of its class.

    Synonyms: T-DXd, T- DXdCategories: MATE 2 Substrates, P-glycoprotein substrates
  6. Drug

    Temsirolimus

    go.drugbank.com/drugs/DB06287
    ApprovedInvestigational

    Temsirolimus was approved by the FDA in late May 2007 as well as the European Medicines Agency (EMEA) on November 2007. … Temsirolimus is a derivative of sirolimus used in the treatment of renal cell carcinoma (RCC). It was developed by Wyeth Pharmaceuticals under the trade name Torisel.

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: TORISEL 25 MG/ML IV INFUZYONLUK COZELTI ICEREN FLAKON, 1 ADET, TORISEL ® 30 MGCONCENTRADO PARA SOLUCION PARA INYECCION(25 MG/ML)
  7. Target

    Chitinase A

    go.drugbank.com/bio_entities/BE0001649
    TargetSerratia marcescens

    Polypeptides: Chitinase A
  8. Target

    Gyrase A

    go.drugbank.com/bio_entities/BE0008384
    TargetMycobacterium tuberculosis

    Polypeptides: Gyrase A
  9. Target

    Cyclin A

    go.drugbank.com/bio_entities/BE0009669
    Target

  10. Target

    Proenkephalin-A

    go.drugbank.com/bio_entities/BE0010659
    TargetHumans

    They play a role in a number of physiologic functions, including pain perception and responses to stress

    Polypeptides: Proenkephalin-A