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Ruxolitinib
go.drugbank.com/drugs/DB08877ApprovedInvestigational[A229708] In 2014, it was approved for the treatment of polycythemia vera in adults who have an inadequate response to or are intolerant of [hydroxyurea] and in 2019, ruxolitinib was approved for use in … [A229938] Ruxolitinib was first approved for the treatment of adult patients with myelofibrosis by the FDA in 2011, followed by EMA's approval in 2012.
Categories: Agents for Dermatitis, Excluding CorticosteroidsDarunavir
go.drugbank.com/drugs/DB01264ApprovedInvestigational[L9227] Darunavir is being studied as a possible treatment for SARS-CoV-2, the coronavirus responsible for COVID-19, due to in vitro evidence supporting its ability to combat this infection. … [L9227] As a second-generation protease inhibitor, darunavir is designed to combat resistance to standard HIV therapy.[A2278,A2281] It was initially approved by the FDA in 2006.
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseRivastigmine
go.drugbank.com/drugs/DB00989ApprovedInvestigationalRivastigmine is a parasympathomimetic or cholinergic agent for the treatment of mild to moderate dementia of the Alzheimer's type.
Categories: Compounds used in a research, industrial, or household settingOvulation Absent
go.drugbank.com/conditions/DBCOND0140456Drugs: LetrozoleSynonyms: Female infertility due to anovulation (disorder)Protein S human
go.drugbank.com/drugs/DB13149ApprovedInvestigationalProtein S human is a vitamin K-dependent plasma glycoprotein which has antcoagulant properties . It serves as a negative feedback mechanism in the coagulation cascade.
Mixtures: OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU, BERIPLEX P/N 500 POWDER FOR SOLUTION FOR INJECTIONAbrocitinib
go.drugbank.com/drugs/DB14973ApprovedInvestigational[A244549] Abrocitinib was approved by the European Commission on December 10, 2021, for the treatment of moderate-to-severe atopic dermatitis (AD) in adults who are candidates for systemic therapy. … [L39784] On January 14, 2022, the FDA approved abrocitinib for the treatment of refractory, moderate-to-severe AD in adults whose disease is not adequately controlled with other systemic drug products,
Categories: Agents for Dermatitis, Excluding CorticosteroidsAcute Non-Lymphocytic Leukemia
go.drugbank.com/conditions/DBCOND0038781Drugs: TioguanineSynonyms: Acute myeloid leukemia, no International Classification of Diseases for Oncology subtypeCutaneous Melanoma
go.drugbank.com/conditions/DBCOND0040978Drugs: IpilimumabSynonyms: Malignant melanoma, no International Classification of Diseases for Oncology subtypeLeukemias
go.drugbank.com/conditions/DBCOND0035632Drugs: Betamethasone · Bupivacaine · Hydrocortisone · Hydrocortisone succinate · Methylprednisolone · Methylprednisolone hemisuccinate +2 moreSynonyms: Leukemia, no International Classification of Diseases for Oncology subtypeMelanoma
go.drugbank.com/conditions/DBCOND0020306Synonyms: Malignant melanoma, no International Classification of Diseases for Oncology subtype