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Cosibelimab
go.drugbank.com/drugs/DB15770ApprovedInvestigationalOn December 13, 2024, cosibelimab was approved by the FDA for the treatment of metastatic or locally advanced cutaneous squamous cell carcinoma [L52690] as the first approved anti-PD-L1 therapy in the
Carbenicillin
go.drugbank.com/drugs/DB00578ApprovedBroad-spectrum semisynthetic penicillin derivative used parenterally. It is susceptible to gastric juice and penicillinase and may damage platelet function.
Categories: combinations of penicillins, Penicillin GFollitropin
go.drugbank.com/drugs/DB00066ApprovedInvestigationalStructural analysis shows that the amino acid sequence of follitropin beta is identical to that of natural human follicle stimulating hormone (FSH). … Follitropin is a human follicle stimulating hormone (FSH) preparation of recombinant DNA origin, which consists of two non-covalently linked, non-identical glycoproteins designated as the alpha- and beta
Categories: Sex Hormones and Modulators of the Genital SystemEstrone
go.drugbank.com/drugs/DB00655ApprovedEstrone, one of the major mammalian estrogens, is an aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone. It is produced in vivo from androstenedione or from testosterone via estradiol. … It is produced primarily in the ovaries, placenta, and in peripheral tissues (especially adipose tissue) through conversion of adrostenedione.
Categories: Sex Hormones and Modulators of the Genital SystemBamlanivimab
go.drugbank.com/drugs/DB15718ApprovedInvestigationalBamlanivimab consists of two identical light chains of 214 amino acids and two identical heavy chains of 455 amino acids each; the Fc region is unmodified. … [L20979] Based on phase 2 clinical trial (BLAZE-1) interim results, bamlanivimab was granted Emergency Use Authorization (EUA) by the FDA on November 10, 2020.
Cariprazine
go.drugbank.com/drugs/DB06016ApprovedInvestigational[L40198] Cariprazine has been investigated in a variety of psychiatric disorders, including schizophrenia, bipolar disorders, and major depressive disorder. … [L41670] It is currently used to treat schizophrenia, and manic or mixed episodes and depressive episodes associated with bipolar I disorder.[L41655,L40198]
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: SYMVENU 1.5 MG, SYMVENU 3.0 MGAminohippuric acid
go.drugbank.com/drugs/DB00345ApprovedInvestigationalWithdrawnThe glycine amide of 4-aminobenzoic acid. Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory capacity. [PubChem]
Categories: Compounds used in a research, industrial, or household settingOxtriphylline
go.drugbank.com/drugs/DB01303ApprovedOxtriphylline is the choline salt form of [theophylline]. … It is marketed under the name Choledyl SA, and several forms of oxytriphylline have been discontinued. In the US, oxtriphylline is no longer available.
Categories: combinations of xanthinesPromazine
go.drugbank.com/drugs/DB00420ApprovedVet approvedWithdrawnIt is primarily used in short-term treatment of disturbed behavior and as an antiemetic. It is currently not approved for use in the United States.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: PROMAZINA EGEfgartigimod alfa
go.drugbank.com/drugs/DB15270ApprovedInvestigational[A243759] The production of IgG autoantibodies against acetylcholine receptors (AChRs) is one of the more common pathophysiological mechanisms behind MG, and results in the destruction of these receptors … [A243759,A243784] Efgartigimod alfa is a first-in-class[L39501] antagonist of the neonatal Fc receptor (FcRn) used in the treatment of MG.
Categories: Human Immunoglobulin G