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Hyoscyamine
go.drugbank.com/drugs/DB00424ApprovedInvestigational[A228713] Hyoscyamine is used for a wide variety of treatments and therapeutics due to its antimuscarinic properties.
Mixtures: UR N-C Urinary Antiseptic, PB HyosCategories: Drugs for Functional Gastrointestinal DisordersKetamine
go.drugbank.com/drugs/DB01221ApprovedInvestigationalVet approvedKetamine is an NMDA receptor antagonist with a potent anesthetic effect.[A31869] It was developed in 1963 as a replacement for phencyclidine (PCP) by Calvin Stevens at Parke Davis Laboratories. … It was FDA approved in 1970, and from there, it has been used as an anesthetic for children or patients undergoing minor surgeries but mainly for veterinary purposes.[L1332]
Categories: NMDA Receptor Antagonists, Cytochrome P-450 SubstratesLapatinib
go.drugbank.com/drugs/DB01259ApprovedInvestigationalLapatinib is an anti-cancer drug developed by GlaxoSmithKline (GSK) as a treatment for solid tumours such as breast and lung cancer. … It was approved by the FDA on March 13, 2007, for use in patients with advanced metastatic breast cancer in conjunction with the chemotherapy drug capecitabine.
Categories: Human epidermal growth factor receptor 2 (HER2) tyrosine kinase inhibitors, P-glycoprotein inhibitorsPI-166
go.drugbank.com/drugs/DB05859ExperimentalPI-166 is a small organic compound with specific avidity to liver cancer cells.
Rilzabrutinib
go.drugbank.com/drugs/DB17709ApprovedInvestigationalRilzabrutinib is an oral, reversible, covalent inhibitor of Bruton's tyrosine kinase [A259078, L53738] that was approved by the FDA on August 29, 2025, for the treatment of persistent and chronic immune … [L53743] ITP is an autoimmune disorder characterized by low platelet count.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesPeanut oil
go.drugbank.com/drugs/DB13964ApprovedWithdrawn[A33169] Under the FDA, peanut oil is categorized as an approved inactive ingredient for its use in drug products. … The kernels are consumed roasted but a large percentage is used for the production of vegetable oil.
Miglustat
go.drugbank.com/drugs/DB00419ApprovedInvestigationalIt inhibits the enzyme glucosylceramide synthase, an essential enzyme for the synthesis of most glycosphingolipids. … Miglustat was first developed as an anti-HIV agent in the 1990s.
Peramivir
go.drugbank.com/drugs/DB06614ApprovedInvestigationalfor no more than two days. … Peramivir is an antiviral agent developed by Biocryst Pharmaceuticals to treat influenza A/B.
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic Use5-hydroxytryptamine receptor 4
go.drugbank.com/bio_entities/BE0000084TargetHumansG protein-coupled receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone and a mitogen (PubMed:10821780, PubMed:16102731, PubMed:35714614, PubMed
Polypeptides: 5-hydroxytryptamine receptor 4Synonyms: Serotonin receptor 4