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Hydroxyzine
go.drugbank.com/drugs/DB00557ApprovedInvestigationalHydroxyzine is a first-generation histamine H1-receptor antagonist of the dephenylmethane and piperazine classes that exhibits sedative, anxiolytic, and antiemetic properties. It was first developed in 1955, and has since remained a rela...
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: Nu-hydroxyzineCyclopentamine
go.drugbank.com/drugs/DB08999ApprovedWithdrawnIt has been widely discontinued due to the safety, effectiveness, and availability of a similar drug, propylhexedrine.
Chloramphenicol succinate
go.drugbank.com/drugs/DB07565Approved[A204065] Use of chloramphenicol succinate and chloramphenicol has decreased due to the risk of potentially fatal blood dyscrasias.
Categories: P-glycoprotein substrates, P-glycoprotein substrates with a Narrow Therapeutic IndexEtorphine
go.drugbank.com/drugs/DB01497ExperimentalIllicitVet approvedA narcotic analgesic morphinan used as a sedative in veterinary practice. In certain countries, etorphine is classified as a Schedule 1 drug and hence, in these countries, it can be used legally only by health professionals and for resea...
Potassium sulfate
go.drugbank.com/drugs/DB14499ApprovedMixtures: VINATAL DHA CAPSULA DE GELATINA BLANDAXenon Xe-129
go.drugbank.com/drugs/DB17386ApprovedInvestigationalLung MRIs are challenging due to the low proton density of this tissue, as well as the presence of artifacts due to respiration and cardiovascular pulsation movement and air–tissue interfaces. … [Helium-3] (He-3) is the one most commonly used due to its strong signal and favorable safety profile, but its use in other applications has affected its availability.
Synonyms: Xenon, isotope of mass 129m(8.88 d)Vanadium
go.drugbank.com/drugs/DB13971ApprovedMixtures: Liquid Opti-minplex +d, Db-7 Dietary SupplementTemafloxacin
go.drugbank.com/drugs/DB01405ApprovedWithdrawnIt was first approved for use in the U.S. market in 1992, but was withdrawn shortly due to the reports of serious adverse reactions, such as allergic reactions and hemolyric anemia, resulting in three
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsLutein
go.drugbank.com/drugs/DB00137ApprovedNutraceuticalLutein is an xanthophyll and one of 600 known naturally occurring carotenoids. Lutein is synthesized only by plants and like other xanthophylls is found in high quantities in green leafy vegetables such as spinach, kale and yellow carrot...
Captopril
go.drugbank.com/drugs/DB01197ApprovedInvestigationalCaptopril is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE), the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and is a key component of the r...
Categories: P-glycoprotein inhibitorsSynonyms: D-2-methyl-3-mercaptopropanoyl-L-proline, D-3-mercapto-2-methylpropanoyl-L-proline