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Displaying results 1861 - 1870 of 10000 in total
  1. Drug

    SNX-5422

    go.drugbank.com/drugs/DB06070
    Investigational

    SNX-5422 is a synthetic, novel, small molecule Hsp90 Inhibitor. … As an oral formulation that demonstrates strong efficacy and tolerability, SNX-5422 is positioned as a breakthrough therapy with broad applicability across a wide range of cancers.

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  2. Drug

    Cholestyramine

    go.drugbank.com/drugs/DB01432
    ApprovedInvestigational

    Cholestyramine resin is quite hydrophilic, but insoluble in water. … Cholestyramine or colestyramine is a bile acid sequestrant. Bile acid sequestrants are polymeric compounds which serve as ion exchange resins.

    Categories: Compounds used in a research, industrial, or household setting, Ion Exchange ResinsProducts: ANTILIP GRANULADO EN SACHET, PHL-cholestyramine Light - 210g Tin
  3. Drug

    Delamanid

    go.drugbank.com/drugs/DB11637
    ApprovedInvestigational

    Multidrug-resistant tuberculosis may also require more than 2 years of chemotherapy and second-line therapies with narrow therapeutic index [A31968]. … It is used in the treatment of multidrug-resistant and extensively drug-resistant tuberculosis (TB) in a combination regimen.

    Synonyms: (2R)-2-methyl-6-nitro-2-((4-(4-(4-(trifluoromethoxy)phenoxy)piperidin-1-yl)phenoxy)methyl)-2,3-dihydroimidazo(2,1-B)(1,3)oxazole, (R)-2-methyl-6-nitro-2-{4-[4-(4-trifluoromethoxyphenoxy)piperidin-1-yl]phenoxymethyl}-2,3-dihydroimidazo[2,1-b]oxazoleCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  4. Drug

    Colestipol

    go.drugbank.com/drugs/DB00375
    Approved

    [FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia … [FDA Label, F4555, F4567, L6262] In particular, as colestipol's general mechanism of action ultimately results in the decreased absorption and enhanced secretion of bile acids and lipids in the feces

    Synonyms: Copolymer of bis(2-aminoethyl)amine and 2-(chloromethyl)oxiraneCategories: Compounds used in a research, industrial, or household setting
  5. Pathway

    Lafutidine H2 Anti-Histamine Action Pathway

    smpdb.ca/view/SMP0051038
    Drug action

    Lafutidine (also known as INN) is a second generation histamine H2 receptor antagonist that can be used for treating ulcers and reflux. Inhibition of histamine H2 receptor can inhibit histamine-stimulated gastric acid secretion which wil...

    Drugs: ATP · Potassium cation · Zinc · Acetylcholine · Lafutidine
    Enzymes: Potassium voltage-gated channel subfamily E member 2
  6. Pathway

    Betamethasone phosphate Action Pathway

    smpdb.ca/view/SMP0126180
    Drug action

    Betamethasone phosphate is a prodrug that is rapidly metabolized to betamethasone. It is used to treat many inflammatory conditions like allergic states, dermatologic diseases, hematologic disorders, renal diseases, respiratory diseases,...

    Drugs: Glutathione · Betamethasone · Dinoprostone · Calcium · Prostaglandin D2 · Mesoheme +3 more
    Enzymes: Prostaglandin E synthase
  7. Drug

    Bronopol

    go.drugbank.com/drugs/DB13960
    Approved

    L4873] and in other products where it may not primarily be used in the role of a non-medicinal preservative antimicrobial [L4874]. … First synthesized in 1897, bronopol was primarily used as a preservative for pharmaceuticals and was registered in the United States in 1984 for use in industrial bactericides, slimicides and preservatives

    Synonyms: 2-Bromo-2-nitropropane-1,3-diol, 2-Nitro-2-bromo-1,3-propanediolCategories: Compounds used in a research, industrial, or household setting
  8. Drug

    Sodium molybdate

    go.drugbank.com/drugs/DB14496
    Approved

    Mixtures: Tracel Injektionslösung in einer Fertigspritze, Addamel NProducts: GENERADOR MON TEK99 MO /TC 99 M
  9. Drug

    Tetrofosmin

    go.drugbank.com/drugs/DB11180
    Approved

    Tetrofosmin is used in conjunction with technetium Tc-99m as a radiopharmaceutical.[A7788] … It presents a molecular formula of 1,2-bis(bis(2-ethoxyethyl)phosphino)ethane. Tetrofosmin is part of the group of diphosphines.

    Mixtures: Tetrofosmin ROTOP 0,23 mg Kit für ein radioaktives ArzneimittelCategories: P-glycoprotein substrates
  10. Drug

    Reslizumab

    go.drugbank.com/drugs/DB06602
    ApprovedInvestigational

    Patients often experience persistent or exacerbating symptoms overtime despite conventional first-line therapies available. … Reslizumab is a humanized interleukin-5 (IL-5) antagonist monoclonal antibody (IgG4 kappa) that is produced by recombinant DNA technology in murine myeloma non-secreting 0 (NS0) cells.

    Categories: Interleukin-5 Antagonist