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TAS-106
go.drugbank.com/drugs/DB06656InvestigationalTAS-106 is a new nucleoside antimetabolite. TAS-106 has demonstrated strong antitumor activity without serious toxicity in nude rat models bearing human tumours [A31693].
Categories: Heterocyclic Compounds, 1-RingSynonyms: 4-Amino-1-((2R,3R,4R,5R)-4-ethynyl-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl)pyrimidin-2-one, 3'-C-EthynylcytidineRostaporfin
go.drugbank.com/drugs/DB06659InvestigationalCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds with 4 or More RingsLixivaptan
go.drugbank.com/drugs/DB06666InvestigationalCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingGolimumab
go.drugbank.com/drugs/DB06674ApprovedInvestigationalIn the U.S. and Canada, golimumab is marketed under the brand name Simponi®. The FDA label includes a black box warning of serious infections and malignancy. … treatment in patients with active psoriatic arthritis (PsA), (iii) as a single agent in patients with active ankylosing spondylitis (AS), and (iv) as a single agent in patients with moderate to severe
Products: SIMPONI 50MG ILO I E FER, SIMPONI® IVAmediplase
go.drugbank.com/drugs/DB06679ExperimentalAmediplase is a recombinant chimeric plasminogen activator, consisting of the kringle 2 domain from the A-chain of tissue plasminogen activator (t-PA) and the carboxy terminal region of pro-urokinase.
Nitrous oxide
go.drugbank.com/drugs/DB06690ApprovedInvestigationalVet approvedAt room temperature, it is a colorless non-flammable gas, with a pleasant, slightly sweet odor and taste. It is used in surgery and dentistry for its anesthetic and analgesic effects. … Nitrous oxide, commonly known as "laughing gas", is a chemical compound with the chemical formula N2O.
Mixtures: OXICALM®, OXICALM®Products: N/AMevastatin
go.drugbank.com/drugs/DB06693ExperimentalMevastatin or compactin is a cholesterol-lowering agent isolated from <i>Penicillium citinium</i>. … Mevastatin is a competitive inhibitor of HMG-Coenzyme A (HMG-CoA) reductase with a binding affinity 10,000 times greater than the HMG-CoA substrate itself.
Isometheptene
go.drugbank.com/drugs/DB06706ApprovedIsometheptene is a sympathomimetic drug that causes vasoconstriction. It is used for treating migraines and tension headaches.
Mixtures: CAFETRIN ®, ANTIALGINA®Categories: Adrenergic alpha-1 Receptor AgonistsLevonordefrin
go.drugbank.com/drugs/DB06707ApprovedInvestigationalLevonordefrin acts as a topical nasal decongestant and vasoconstrictor, most often used in dentistry.
Mixtures: Scandonest 2% L, Scandonest LSynonyms: L-Nordefrin, L-alpha-methylnoradrenaline