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Boceprevir
go.drugbank.com/drugs/DB08873ApprovedWithdrawnwith [DB00811], [DB00008], and [DB00022] as first line therapy for Hepatitis C [A19593]. … Boceprevir is an inhibitor of NS3/4A, a serine protease enzyme, encoded by HCV genotypes 1 and 4 [synthesis].
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsProducts: VICTRELIS ® CAPSULAS 200 MG (MOLECULA PROTEGIDA)Praziquantel
go.drugbank.com/drugs/DB01058ApprovedInvestigationalVet approved[A263201] The efficacy of praziquantel in treating parasitic flatworms infection with low cost (~US$0.20 drug cost to treat a child) makes it an integral to WHO's plan to eliminate schistosomiasis by 2030 … [A263206,A263211] Despite being approved since 1980, the exact mechanism of action is yet to be elucidated.[A263211]
Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 SubstratesProducts: DISTOCIDE TABLET 600 mgJosamycin
go.drugbank.com/drugs/DB01321InvestigationalA macrolide antibiotic from Streptomyces narbonensis. The drug has antimicrobial activity against a wide spectrum of pathogens.
Products: Josalid 500 mg - Filmtabletten, Josalid 250 mg/5 ml - Saft für KinderFerrous ascorbate
go.drugbank.com/drugs/DB14490ApprovedWithdrawnSynonyms: Iron(2+) L-ascorbateCategories: Compounds used in a research, industrial, or household settingOxidronic acid
go.drugbank.com/drugs/DB14159ApprovedProducts: TECHNESCAN HDP FOR INJECTION 3 mg/vial, TECHNESCAN HDP POWDER FOR INJECTION 3.15 mg/vialMolsidomine
go.drugbank.com/drugs/DB09282ApprovedWithdrawnInterestingly, it is being studied as being a preventive measure in cerebral infarction [A31932]. … Molsidomine is an orally active, long-acting vasodilator, which belongs to the class of medications known as syndnones.
Categories: Vasodilators Used in Cardiac DiseasesProducts: Molsidolat 4 mg Tabletten, Nesidom 16 mg - RetardtablettenMifamurtide
go.drugbank.com/drugs/DB13615ApprovedInvestigationalWhile about 90% of patients with newly diagnosed osteosarcoma may achieve complete remission from first-line therapies, the prognosis is still poor for patients with non-metastatic osteosarcoma with lower … 5-year event-free survival.
Products: MEPACT 4 MG INFÜZYONLUK DISPERSIYON KONSANTRESI IÇIN TOZ ,FLAKON, 1 ADETFenspiride
go.drugbank.com/drugs/DB08979InvestigationalIt is approved for use in Russia for the treatment of acute and chronic inflammatory diseases of ENT organs and the respiratory tract (like rhinopharyngitis, laryngitis, tracheobronchitis, otitis and sinusitis … Fenspiride is an oxazolidinone spiro compound used as a drug in the treatment of certain respiratory diseases.
Products: OXOFEN 2 MG/ML ŞURUP ,150 ML, PASFEN 2MG/ML ŞURUPSodium acetate
go.drugbank.com/drugs/DB09395ApprovedInvestigationalIt can be used also in metabolic acidosis and for urine alkalinization. … Medically, sodium acetate is important component as an electrolyte replenisher when given intravenously. It is mainly indicated to correct sodium levels in hyponatremic patients.
Mixtures: POLİNUTHREE EN-550 ELEKTROLİTLİ AMİNOASİT ÇÖZELTİSİ, GLUKOZ ÇÖZELTİSİ, VE LİPİD EMÜLSİYONU, 1000 ML, POLİNUTHREE EN-1000 ELEKTROLİTLİ AMİNOASİT ÇÖZELTİSİ, GLUKOZ ÇÖZELTİSİ, VE LİPİD EMÜLSİYONU, 1000 MLProducts: Sodium Acetate Inj 328mg/ml USPAcenocoumarol
go.drugbank.com/drugs/DB01418ApprovedInvestigationalPatients on acenocoumarol are prohibited from giving blood. … Acenocoumarol is a coumarin derivative used as an anticoagulant. Coumarin derivatives inhibit the reduction of vitamin K by vitamin K reductase.
Categories: Heterocyclic Compounds, 2-Ring, 4-HydroxycoumarinsSynonyms: 4-Hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-2H-chromen-2-one, 4-Hydroxy-3-(1-(4-nitrophenyl)-3-oxobutyl)-2H-1-benzopyran-2-one