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Cantharidin
go.drugbank.com/drugs/DB12328ApprovedInvestigational[L47496] The approval was based on positive results from 2 phase III trials, CAMP-1 and CAMP-2, where 46% and 52% of patients treated with cantharidin achieved complete molluscum clearance, respectively … [A32891, A32892] For its natural purpose, the male blister beetle secretes and presents the cantharidin to a female beetle as a copulatory gift during mating.
Mixtures: CANTHACUR PS %1,%5,%30 TOPIKAL SOLUSYON 7,5 ML, Cantharidin 1% / Podophyllum Resin 5% / Salicylic Acid 30%Categories: Heterocyclic Compounds, 2-Ring, Compounds used in a research, industrial, or household settingCholine salicylate
go.drugbank.com/drugs/DB14006ApprovedNutraceuticalThis drug is also a main ingredient in teething gels to relieve pains associated with tooth growth in the infant population [L2134].
Products: DENCOL JEL SPREY, 20 G, Colident %8.71 jel sprey, 20 GAmyl Nitrite
go.drugbank.com/drugs/DB01612ApprovedIts use as a prescription medicine comes from its ability to lower blood pressure. As an inhalant, it also has psychoactive effect which has led to illegal drug use.
Synonyms: 1-nitropentane, n-Amyl nitriteProducts: AMYL NITRITE INHALANT USP 0.3 ml/ampoule, Amyl Nitrite Vitrellae Bpc Liq 0.33 Ml/capVonoprazan
go.drugbank.com/drugs/DB11739ApprovedInvestigationalVonoprazan is a potassium-competitive acid blocker (PCAB) that inhibits H<sup>+</sup>, K<sup>+</sup>-ATPase-mediated gastric acid secretion. … [A253702] Furthermore, vonoprazan is 350-times more potent than the proton-pump inhibitor [lansoprazole], thanks to its ability to accumulate in the gastric corpus mucosa, specifically in the parietal
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 SubstratesSynonyms: 1-[5-(2-fluorophenyl)-1-pyridin-3-ylsulfonylpyrrol-3-yl]-N-methylmethanamineFluorodopa (18F)
go.drugbank.com/drugs/DB13848ApprovedInvestigationalFluorodopa F 18 is a fluorinated analog of [levodopa] used as a diagnostic agent for positron emission tomography (PET) in the evaluation of Parkinsonian syndromes. … [L12849] Fluorodopa F 18 PET is used adjunctly with other diagnostic investigations and serves primarily to visualize dopaminergic nerve terminals in the striatum.[L12849]
Synonyms: L-6-(18F)Fluoro-DOPA, 6-Fluoro-(18F)-L-3,4-DihydroxyphenylalanineProducts: Dopaview 222 MBq/ml Injektionslösung, IASOdopa 0,3 GBq/ml - Konzentrat zur Herstellung einer InjektionslösungElastin (human)
go.drugbank.com/drugs/DB15364ExperimentalElastin (human) is under investigation in clinical trial NCT01466413 (Two Formulations of ELAPR Compared to Restylane® Vital Light Following Repeat Implants in the Upper Arm Dermis).
Synonyms: SH-POLYPEPTIDE-50Human cytomegalovirus immune globulin
go.drugbank.com/drugs/DB13886ApprovedInvestigationalIt contains purified immunoglobulin G (IgG) antibodies targeting cytomegalovirus (CMV)[FDA label]. … The seroprevalence of antibodies in adults ranges from 40-100 % with an inverse correlation to socioeconomic status.
Categories: Immunoglobulin G, Human Immunoglobulin GProducts: MEGALOTECT CP SOLUTION FOR INFUSION 100 U/MLDesfesoterodine
go.drugbank.com/drugs/DB15578InvestigationalDesfesoterodine is a metabolite of [tolterodine].
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesSynonyms: 5-HydroxymethyltolterodineCoagulation factor X human
go.drugbank.com/drugs/DB13148ApprovedInvestigationalCoagulation Factor X (Human) solution is approved by the FDA for intravenous injection under the market name Coagadex which contains normally 100 IU/mL of coagulation Factor X derived from healthy donors … Inherited factor X deficiency is a rare autosomal recessive bleeding disorder that is estimated to occur in 1:1 000 000 individuals up to 1:500 carriers [A31471].
Mixtures: COFACT 500 IU/20 ML IV ENJEKSIYON IÇIN TOZ IÇEREN FLAKON, 1 ADET, COFACT 250 IU/10 ML IV ENJEKSIYON IÇIN TOZ IÇEREN FLAKON, 1 ADETCategories: Factor X, Factor X, agonistsCilgavimab
go.drugbank.com/drugs/DB16393ApprovedInvestigational[A243356, A243361] Cilgavimab (formerly AZD1061) is a recombinant monoclonal antibody produced in Chinese hamster ovary (CHO) cells derived from a neutralizing antibody isolated from a patient with a natural … SARS-CoV-2, the causative agent of COVID-19, enters cells via the interaction between the trimeric spike (S) glycoprotein and host cell angiotensin-converting enzyme 2 (ACE2).