Search
Clioquinol
go.drugbank.com/drugs/DB04815ApprovedVet approvedWithdrawnClioquinol was withdrawn in 1983 due to neurotoxicity.
Mixtures: PRECORT-A KREM, Dermasorb AF Complete KitEtifoxine
go.drugbank.com/drugs/DB08986ApprovedWithdrawnIt does not bind to the benzodiazepine receptor though the effects are similar to that of benzodiazepines. It is more effective than lorazepam as an anxiolytic, and has fewer side effects. … Etifoxine is an anxiolytic and anticonvulsant drug developed by Hoechst in the 1960s. It is used in anxiety disorders and to promote peripheral nerve healing.
Mangafodipir
go.drugbank.com/drugs/DB06796ApprovedInvestigationalWithdrawnMangafodipir is a contrast agent used as a diagnostic tool administered intravenously to enhance contrast in magnetic resonance imaging (MRI) of the liver and pancreas. … The contrast agent is present as mangafodipir trisodium marketed under the name Teslascan.
Categories: Compounds used in a research, industrial, or household settingLenograstim
go.drugbank.com/drugs/DB13144ApprovedWithdrawnLenograstim is a recombinant granulocyte colony-stimulating factor used as an immunostimulating agent.
Vilanterol
go.drugbank.com/drugs/DB09082ApprovedInvestigational[A259966] Additionally, vilanterol demonstrated a significantly longer duration of action than salmeterol, with the bronchodilator effect still apparent at 22h. … [A259961] Vilanterol was designed based on the salmeterol molecular scaffold, particularly as a antedrug analog of salmeterol modification by modifying the salmeterol molecule to create homochiral compounds
Belatacept
go.drugbank.com/drugs/DB06681ApprovedInvestigationalStructurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight of 92,300 Da and it is a homodimer of two homologous polypeptide chains of 357 amino acids each. … It is produced through recombinant DNA technology in mammalian CHO cells. The drug has activity as a selective co-stimulation modulator with inhibitory activity on T lymphocytes.
Categories: Selective T Cell Costimulation Blocker, T Lymphocyte Costimulation Activity BlockadeRemestemcel-L
go.drugbank.com/drugs/DB13973ApprovedInvestigationalWithdrawnIn clinical studies, patients treated with remestemcel-L demonstrated an improvement in their aGvHD and improved survival rates at subsequent days following intravenous infusion [L11022]. … with first-line therapies, putting them in a risk for poor outcomes and creating a significant clinical challenge [A31818].
Indigotindisulfonic acid
go.drugbank.com/drugs/DB11577ApprovedInvestigationalIndigotindisulfonic acid is a blue-colored dye with a variety of uses. … This compound is an acid-base indicator and is used in the production of food colorants and pH tests.
Categories: Compounds used in a research, industrial, or household settingMisoprostol
go.drugbank.com/drugs/DB00929ApprovedInvestigationalMisoprostol is a prostaglandin analog used to reduce the risk of NSAID related ulcers, manage miscarriages, prevent post partum hemorrhage, and also for first trimester abortions.
Mixtures: Act Diclo-miso, Act Diclo-misoTeplizumab
go.drugbank.com/drugs/DB06606ApprovedInvestigationalTeplizumab was designed as an Fc-non-binding antibody in order to reduce the incidence of CRS. … [A241480,A241500] Targeting T cells can be achieved through antibodies against the T cell receptor (TCR) component CD3.