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Displaying results 1921 - 1930 of 1993 in total
  1. Drug

    Brompheniramine

    go.drugbank.com/drugs/DB00835
    Approved

    Histamine H1 antagonist used in treatment of allergies, rhinitis, and urticaria.

    Mixtures: J-tan D PdProducts: J-tan Pd
  2. Target

    Proto-oncogene tyrosine-protein kinase ROS

    go.drugbank.com/bio_entities/BE0009534
    TargetHumans

    Receptor tyrosine kinase (RTK) that plays a role in epithelial cell differentiation and regionalization of the proximal epididymal epithelium. NELL2 is an endogenous ligand for ROS1.

    Synonyms: c-Ros receptor tyrosine kinase, Receptor tyrosine kinase c-ros oncogene 1
  3. Target

    Sodium-dependent phosphate transporter 1

    go.drugbank.com/bio_entities/BE0005055
    TransporterHumans

    Sodium-phosphate symporter which preferentially transports the monovalent form of phosphate with a stoichiometry of two sodium ions per phosphate ion (PubMed:11009570, PubMed:16790504, PubMed:17494632, PubMed:19726692, PubMed:7929240, Pu...

    Synonyms: Leukemia virus receptor 1 homolog, Gibbon ape leukemia virus receptor 1
  4. Target

    Platelet glycoprotein 4

    go.drugbank.com/bio_entities/BE0010538
    TargetTransporterHumans

    Multifunctional glycoprotein that acts as a receptor for a broad range of ligands. … Receptor for thrombospondins, THBS1 and THBS2, mediating their antiangiogenic effects (By similarity).

    Synonyms: Thrombospondin receptor, Platelet collagen receptor
  5. Drug

    AV608

    go.drugbank.com/drugs/DB05072
    Investigational

    AV608 is a NK-1 antagonist. It is developed for the treatment of Social anxiety disorder (SAD), irritable bowel syndrome (IBS) and overactive bladder (OAB).

  6. Target

    Activated CDC42 kinase 1

    go.drugbank.com/bio_entities/BE0000772
    TargetHumans

    Contributes to the control of AXL receptor levels. … Implicated in trafficking and clathrin-mediated endocytosis through binding to epidermal growth factor receptor (EGFR) and clathrin.

    Synonyms: Tyrosine kinase non-receptor protein 2
  7. Target

    Integrin alpha-M

    go.drugbank.com/bio_entities/BE0010412
    TargetHumans

    It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. … Integrin ITGAM/ITGB2 is also a receptor for ICAM1 ligand ensuring adhesion between stimulated neutrophils and stimulated endothelial cells (PubMed:1980124).

    Synonyms: Neutrophil adherence receptor, Leukocyte adhesion receptor MO1
  8. Target

    High affinity cationic amino acid transporter 1

    go.drugbank.com/bio_entities/BE0000212
    TargetTransporterHumans

    High-affinity, low capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine) in non-hepatic tissues

    Synonyms: Ecotropic retrovirus receptor homolog, Ecotropic retroviral leukemia receptor homolog
  9. Drug

    Umbilical Cord Blood Hematopoietic Stem Cells

    go.drugbank.com/drugs/DB15723
    Investigational

    HUCBC CD34+ cells are cultured with various cytokines and interleukins to give rise to various cell types, from red blood cells, to B-, T-, and Natural Killer Cells.

  10. Target

    Hepatocyte nuclear factor 4-gamma

    go.drugbank.com/bio_entities/BE0003179
    TargetHumans

    Transcription factor. Has a lower transcription activation potential than HNF4-alpha

    Synonyms: Nuclear receptor subfamily 2 group A member 2