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Human C1-esterase inhibitor
go.drugbank.com/drugs/DB06404ApprovedInvestigationalC1 Esterase Inhibitor (Human) is composed of purified endogenous complement component-1 esterase inhibitor (hC1INH) isolated from human plasma. The primary function of endogenous C1INH is to regulate the activation of the complement and ...
Etonogestrel
go.drugbank.com/drugs/DB00294ApprovedInvestigationalEtonogestrel molecule is a 3-ketodesogestrel or 19-nortestosterone which is a synthetic biologically active metabolite of progestin desogestrel. The first product including etonogestrel was developed by the Merck subsidiary Organon and F...
Lubiprostone
go.drugbank.com/drugs/DB01046ApprovedInvestigationalLubiprostone is a medication used in the management of idiopathic chronic constipation. A prostaglandin E1 derivative, lubiprostone is a bicyclic fatty acid that activates ClC-2 chloride channels located on the apical side of the gastroi...
Cladribine
go.drugbank.com/drugs/DB00242ApprovedInvestigational[A350] Cladribine was first approved in the United States in 1993 [A263713] initially as a treatment for a number of hematological malignancies; currently, it is approved for the treatment of hairy cell
Sutilain
go.drugbank.com/drugs/DB09379ApprovedWithdrawnIt is currently discontinued.[L2368] … It is able to dissolve the intercellular matrix which helps with desquamation.
Rilzabrutinib
go.drugbank.com/drugs/DB17709ApprovedInvestigationalRilzabrutinib is thought to work by dual mechanisms of action in ITP: It attenuates macrophage (Fcγ receptor)-mediated platelet destruction and reduces the production of pathogenic autoantibodies.
Xylometazoline
go.drugbank.com/drugs/DB06694ApprovedIn some countries, it is available as combination products with [ipratropium], [domiphen], or [dexpanthenol].
Products: MEIN NASENSPRAY VITASeproxetine
go.drugbank.com/drugs/DB06731ExperimentalIt is a selective serotonin reuptake inhibitor (SSRI). It is an active metabolite of fluoxetine.
Hemoglobin
go.drugbank.com/drugs/DB04945ApprovedInvestigationalWithdrawnIt consists primarily of globin and heme.
Nilotinib
go.drugbank.com/drugs/DB04868ApprovedInvestigationalNilotinib, also known as AMN107, is a tyrosine kinase inhibitor under investigation as a possible treatment for chronic myelogenous leukemia (CML). A Phase I clinical trial in 2006 showed that this drug was relatively safe and offered si...