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Displaying results 1961 - 1970 of 10000 in total
  1. Drug

    Olezarsen

    go.drugbank.com/drugs/DB18728
    ApprovedInvestigational

    Olezarsen is an antisense oligonucleotide that targets the messenger RNA (mRNA) for apolipoprotein C-III (APOC3, apoC-III),[L52033] which is a key regulator of triglyceride levels in plasma, in the liver … [L52028] It is also being investigated for the treatment of hyperlipidemia.[A264898,A264903]

  2. Drug

    Nylidrin

    go.drugbank.com/drugs/DB06152
    ApprovedWithdrawn

    Therefore, the FDA has withdrawn nylidrin from the U.S. market [L2286]. … Nylidrin is a peripheral vasodilator.

  3. Drug

    Indapamide

    go.drugbank.com/drugs/DB00808
    ApprovedInvestigational

    [A204155] Characterized by an office blood pressure of ≥140/90, hypertension is pervasive and impacts an estimated 25% of adults globally. … agents may be required in order to achieve blood pressure targets.

    Mixtures: CARDIK - IN® 160/2.5, CARDIK - IN® 160/2.5
  4. Drug

    Camizestrant

    go.drugbank.com/drugs/DB19218
    ApprovedInvestigational

    Camizestrant is an oral selective estrogen receptor degrader (SERD) and estrogen receptor (ER) antagonist used in combination with a CDK4/6 inhibitor to treat hormone receptor-positive, HER2-negative locally … [L64094,L64107] In pre- or peri-menopausal women and in men, camizestrant plus a CDK4/6 inhibitor is combined with an LHRH agonist or antagonist.

    Categories: Estrogen Receptor Antagonists, Selective Estrogen Receptor Degraders
  5. Drug

    Estrapronicate

    go.drugbank.com/drugs/DB20501
    Experimental

    Estrapronicate is a small molecule drug. Estrapronicate has a monoisotopic molecular weight of 433.23 Da.

    Categories: Estradiol Congeners
  6. Drug

    Cetyl alcohol

    go.drugbank.com/drugs/DB09494
    Approved

    Mainly it is used as an opacifier, emulsifier, and thickening agent that alter the thickness of the liquid, and increase and stabilize the foaming capacity. … Cetyl alcohol, also known as 1-hexadecanol or n-hexadecyl alcohol, is a 16-C fatty alcohol with the chemical formula CH3(CH2)15OH. It can be produced from the reduction of palmitic acid.

  7. Drug

    L-arginine

    go.drugbank.com/drugs/DB17289
    ApprovedInvestigationalNutraceutical

    Mixtures: Aminosyn II In Dextrose Injection, Aminosyn II In Dextrose Injection
  8. Target

    Peroxisome proliferator-activated receptor alpha

    go.drugbank.com/bio_entities/BE0000071
    TargetHumans

    Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids.

    Polypeptides: Peroxisome proliferator-activated receptor alphaSynonyms: Nuclear receptor subfamily 1 group C member 1
  9. Target

    Glutamate receptor ionotropic, NMDA 1

    go.drugbank.com/bio_entities/BE0000365
    TargetHumans

    Component of N-methyl-D-aspartate (NMDA) receptors (NMDARs) that function as heterotetrameric, ligand-gated cation channels with high calcium permeability and voltage-dependent block by Mg(2+) (PubMed:21376300, PubMed:26875626, PubMed:26...

    Polypeptides: Glutamate receptor ionotropic, NMDA 1Synonyms: Glutamate [NMDA] receptor subunit zeta-1, N-methyl-D-aspartate receptor subunit NR1
  10. Target

    Glutamate receptor ionotropic, NMDA 2D

    go.drugbank.com/bio_entities/BE0000396
    TargetHumans

    Component of N-methyl-D-aspartate (NMDA) receptors (NMDARs) that function as heterotetrameric, ligand-gated cation channels with high calcium permeability and voltage-dependent block by Mg(2+) (PubMed:26875626, PubMed:27616483, PubMed:28...

    Polypeptides: Glutamate receptor ionotropic, NMDA 2DSynonyms: N-methyl D-aspartate receptor subtype 2D, Glutamate [NMDA] receptor subunit epsilon-4