Search

Displaying results 1961 - 1970 of 10000 in total
  1. Drug

    Avacincaptad pegol

    go.drugbank.com/drugs/DB15165
    ApprovedInvestigational

    Avacincaptad pegol is an RNA aptamer covalently bound to a branched polyethylene glycol (PEG) molecule. … [A260801] Avacincaptag pegol was approved by the FDA on August 4, 2023, under the brand name IZERVAY for the treatment of GA secondary to AMD.

  2. Target

    Carbonyl reductases (CBRs)

    go.drugbank.com/bio_entities/BE0010129
    EnzymeHumans

    Can convert prostaglandin E to prostaglandin F2-alpha (By similarity). Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates.

    Synonyms: Prostaglandin-E(2) 9-reductase
  3. Indication

    Pulmonary Embolism

    go.drugbank.com/conditions/DBCOND0027915
    Drugs: Acenocoumarol · Apixaban · Dabigatran etexilate · Dextran · Edoxaban · Enoxaparin +7 more
    Synonyms: PE, PE - Pulmonary Embolism
  4. Pathway

    Difluprednate Action Pathway

    smpdb.ca/view/SMP0126254
    Drug action

    Difluprednate, also known as Durezol, is a topical corticosteroid indicated for the symptomatic treatment of inflammation and pain associated with ocular surgery. This drug is administered as an ophthalmic emulsion. It is a butyrate este...

    Drugs: Glutathione · Dinoprostone · Calcium · Prostaglandin D2 · Mesoheme · Prostaglandin G2 +2 more
    Enzymes: Prostaglandin E synthase
  5. Pathway

    Phosphatidylethanolamine Biosynthesis PE(14:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z))

    smpdb.ca/view/SMP0015082
    Metabolic

    Phosphatidylethanolamines (PE) are a class of phospholipids that incorporate a phosphoric acid headgroup into a diacylglycerol backbone.

    Drugs: Choline · Serine · Phosphatidyl serine · ATP · Cytidine-5'-Triphosphate · Ethanolamine +1 more
  6. Pathway

    Phosphatidylethanolamine Biosynthesis PE(14:1(9Z)/22:5(4Z,7Z,10Z,13Z,16Z))

    smpdb.ca/view/SMP0015109
    Metabolic

    Phosphatidylethanolamines (PE) are a class of phospholipids that incorporate a phosphoric acid headgroup into a diacylglycerol backbone.

    Drugs: Choline · Serine · Phosphatidyl serine · ATP · Cytidine-5'-Triphosphate · Ethanolamine +1 more
  7. Pathway

    Phosphatidylethanolamine Biosynthesis PE(16:1(9Z)/22:5(4Z,7Z,10Z,13Z,16Z))

    smpdb.ca/view/SMP0015195
    Metabolic

    Phosphatidylethanolamines (PE) are a class of phospholipids that incorporate a phosphoric acid headgroup into a diacylglycerol backbone.

    Drugs: Choline · Serine · Phosphatidyl serine · ATP · Cytidine-5'-Triphosphate · Ethanolamine +1 more
  8. Pathway

    Phosphatidylethanolamine Biosynthesis PE(16:1(9Z)/22:5(7Z,10Z,13Z,16Z,19Z))

    smpdb.ca/view/SMP0015196
    Metabolic

    Phosphatidylethanolamines (PE) are a class of phospholipids that incorporate a phosphoric acid headgroup into a diacylglycerol backbone.

    Drugs: Choline · Serine · Phosphatidyl serine · ATP · Cytidine-5'-Triphosphate · Ethanolamine +1 more
  9. Pathway

    Phosphatidylethanolamine Biosynthesis PE(18:1(11Z)/20:5(5Z,8Z,11Z,14Z,17Z))

    smpdb.ca/view/SMP0015248
    Metabolic

    Phosphatidylethanolamines (PE) are a class of phospholipids that incorporate a phosphoric acid headgroup into a diacylglycerol backbone.

    Drugs: Choline · Serine · Phosphatidyl serine · ATP · Cytidine-5'-Triphosphate · Ethanolamine +1 more
  10. Pathway

    Phosphatidylethanolamine Biosynthesis PE(18:1(11Z)/22:5(7Z,10Z,13Z,16Z,19Z))

    smpdb.ca/view/SMP0015254
    Metabolic

    Phosphatidylethanolamines (PE) are a class of phospholipids that incorporate a phosphoric acid headgroup into a diacylglycerol backbone.

    Drugs: Choline · Serine · Phosphatidyl serine · ATP · Cytidine-5'-Triphosphate · Ethanolamine +1 more