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Displaying results 11 - 13 of 13 in total
  1. Pathway

    Ethanol Degradation

    smpdb.ca/view/SMP0000449
    Metabolic

    Ethanol metabolism in humans occurs mainly in the liver, though degradation has also been shown in gastric, pancreatic, and lung tissue. Ethanol degradation occurs via four pathways, three of which are oxidative pathways and are depicted...

    Drugs: Adenosine phosphate · NADH · ATP · Ethanol · Zinc · Mesoheme +2 more
  2. Pathway

    Disulfiram Aldehyde Dehydrogenase Inhibitor Action Pathway

    smpdb.ca/view/SMP0122693
    Drug action

    Disulfiram is a carbamate derivative used to treat chronic alcoholism. It irreversibly inhibits aldehyde dehydrogenase in the mitochondrial matrix which converts acetaldehyde to acetic acid causing an accumulation of acetaldehyde. The hi...

    Drugs: Adenosine phosphate · NADH · ATP · Disulfiram · Ethanol · Zinc +3 more
  3. Pathway

    Pentose Phosphate Pathway

    smpdb.ca/view/SMP0000031
    Metabolic

    ;reaction 3 where 6-phosophogluconate dehydrogenase converts 6-phospho-D-gluconate into ribulose 5-phosphate with NADPH formation; reaction 4 where ribulose-phosphate 3-epimerase converts ribulose 5-phosphate … dehydrogenase converts glucose 6-phosphate into D-glucono-1,5-lactone 6-phosphate with NADPH formation; reaction 2 where 6-phosphogluconolactonase converts D-glucono-1,5-lactone 6-phosphate into 6-phospho-D-gluconate

    Drugs: Adenosine phosphate · ATP · Magnesium cation · Iron · 5-O-phosphono-alpha-D-ribofuranosyl diphosphate · D-glyceraldehyde 3-phosphate +4 more