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Sodium channel protein
go.drugbank.com/bio_entities/BE0009367TargetPediculus humanusMediates the voltage-dependent sodium ion permeability of excitable membranes. … Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their
Polypeptides: Sodium channel proteinSodium/iodide cotransporter
go.drugbank.com/bio_entities/BE0009346TargetTransporterHumansCan also mediate the transport of chlorate, thiocynate, nitrate and selenocynate (PubMed:12488351)
Polypeptides: Sodium/iodide cotransporterSynonyms: Sodium-iodide symporterSodium-dependent multivitamin transporter
go.drugbank.com/bio_entities/BE0000094TargetTransporterHumansSodium-dependent multivitamin transporter that mediates the electrogenic transport of pantothenate, biotin, lipoate and iodide (PubMed:10329687, PubMed:15561972, PubMed:19211916, PubMed:20980265, PubMed … Required for biotin and pantothenate uptake in the intestine across the brush border membrane (PubMed:19211916).
Polypeptides: Sodium-dependent multivitamin transporterSodium/calcium exchanger 1
go.drugbank.com/bio_entities/BE0000986TargetTransporterHumansMediates the exchange of one Ca(2+) ion against three to four Na(+) ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca(2+) levels and Ca(2+)-dependent cellular processes … Required for normal embryonic heart development and the onset of heart contractions (By similarity)
Polypeptides: Sodium/calcium exchanger 1Sodium-dependent dopamine transporter
go.drugbank.com/bio_entities/BE0009676TransporterTargetMouseMediates sodium- and chloride-dependent transport of dopamine (PubMed:10375632, PubMed:12606774). … Also mediates sodium- and chloride-dependent transport of norepinephrine (also known as noradrenaline) (By similarity).
Polypeptides: Sodium-dependent dopamine transporterSodium/glucose cotransporter 4
go.drugbank.com/bio_entities/BE0014888TransporterHumansElectrogenic Na(+)-coupled sugar symporter that may play a primary role in D-mannose and possibly D-fructose and D-glucose transport at the plasma membrane. … Exclusively recognizes sugar substrates having a pyranose ring with an axial hydroxyl group on carbon 2
Polypeptides: Sodium/glucose cotransporter 4Sodium/hydrogen exchanger 2
go.drugbank.com/bio_entities/BE0020524TransporterHumansPlasma membrane Na(+)/H(+) antiporter. Mediates the electroneutral exchange of intracellular H(+) ions for extracellular Na(+) (PubMed:10444453). Major apical Na(+)/H(+) exchanger in the base of the colonic crypt. Controls in the colonic...
Polypeptides: Sodium/hydrogen exchanger 2Function: sodiumSodium-dependent proline transporter
go.drugbank.com/bio_entities/BE0000723TargetHumansBrain specific sodium (and chloride)-dependent proline transporter (PubMed:7651355). … Terminates the action of proline by its high affinity sodium-dependent reuptake into presynaptic terminals (Probable)
Polypeptides: Sodium-dependent proline transporterSodium/myo-inositol cotransporter
go.drugbank.com/bio_entities/BE0009368TransporterHumansAssociates with KCNQ1-KCNE2 channel in the apical membrane of choroid plexus epithelium and regulates the myo-inositol gradient between blood and cerebrospinal fluid with an impact on neuron excitability … Maintains myo-inositol concentration gradient that defines cell volume and fluid balance during osmotic stress, in particular in the fetoplacental unit and central nervous system (By similarity).
Polypeptides: Sodium/myo-inositol cotransporterSynonyms: Sodium/myo-inositol transporter 1