Search
2-Aminoadipic 2-Oxoadipic Aciduria
smpdb.ca/view/SMP0000719DiseaseSymptoms of the disease include mild to severe intellectual disability, developmental delay, ataxia, muscular hypotonia, and epilepsy. However, most cases are asymptomatic.
Drugs: Pyridoxal phosphate · Lysine · Glutamic acid · NADH · Oxogluric acid · Flavin adenine dinucleotide +1 moreTopiramate Action Pathway (New)
smpdb.ca/view/SMP0125139Drug actionTopiramate is an anticonvulsant drug used in the control of epilepsy and in the prophylaxis and treatment of migraines. … Most common adverse effects in epilepsy trials included the involvement of the central nervous system (paresthesia, fatigue, cognitive problems, dizziness, somnolence, psychomotor slowing, memory/concentration
Pyridoxine Dependency with Seizures
smpdb.ca/view/SMP0125701DiseaseThe condition pyridoxine dependent-epilepsy is a condition that sees seizures beginning in infancy. In some cases, the seizures begin before birth.
Drugs: Pyridoxal phosphate · Lysine · Glutamic acid · NADH · Oxogluric acid · Flavin adenine dinucleotide +1 moreLamotrigine Action Pathway
smpdb.ca/view/SMP0126274Drug actionIt is used in the treatment of both epilepsy and as a mood stabilizer in bipolar disorder. … Lamotrigine is a phenyltriazine antiepileptic used to treat some types of epilepsy and bipolar I disorder. It can be found under the brand name Lamictal.
Oxcarbazepine Action Pathway (New)
smpdb.ca/view/SMP0126277Drug actionThe opening and closing of sodium channels allows for the propagation of action potentials along neurons - in epilepsy, these action potentials can occur in excess of that required for normal function,
Ethosuximide Action Pathway
smpdb.ca/view/SMP0126318Drug actionUsed in the treatment of epilepsy.
Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Ethosuximide · Calcium · Magnesium cation +3 moreTrimethadione Action Pathway
smpdb.ca/view/SMP0126340Drug actionDione anticonvulsants are used in the treatment of epilepsy. They act on the central nervous system (CNS) to reduce the number of seizures.
Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Trimethadione · Calcium · Magnesium cation +3 moreGABA-Transaminase Deficiency
smpdb.ca/view/SMP0000351DiseaseSymptoms of this disorder include low muscle tone and psychomotor retardation, as well as potential epilepsy and excessive sleeping.
Diazepam Action Pathway
smpdb.ca/view/SMP0124471Drug actionDue to its effects it's used to treat severe anxiety disorders, short term insomnia, acute repetitive seizures, alcohol withdrawal. and possibly epilepsy.
Metabolsim and Physiological Effects of Argininic acid
smpdb.ca/view/SMP0125504MetabolicArgininic acid is a uremic toxin that is toxic to the nervous system, and it causes various neurlogical disorders such as variable degree of mental retardation, epilepsy and progressive spasticity.
Drugs: Pyridoxal phosphate · Arginine · Aspartic acid · Ornithine · L-Glutamine · Adenosine phosphate +10 more