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Displaying results 11 - 20 of 119 in total
  1. Pathway

    Isocarboxazid Amine Oxidase Norepinephrine Antidepressant Action Pathway

    smpdb.ca/view/SMP0126692
    Drug action

    The first one is found in cells located in the periphery and breakdown serotonin, norepinephrine, epinephrine, dopamine, and tyramine. … The second one, the B isoform, breakdowns phenylethylamine, norepinephrine, epinephrine, dopamine, and tyramine. This isoform is found in the extracellular tissues and mostly in the brain.

    Drugs: Pyridoxal phosphate · Ademetionine · Ascorbic acid · Tyrosine · NADH · Sapropterin +8 more
  2. Pathway

    Phentermine Norepinephrine Reuptake transporter Satiety Action Pathway

    smpdb.ca/view/SMP0126723
    Drug action

    Phentermine is an amine anorectic agent used in weight reduction in cases of exogenous obesity as an adjunct or alone. It is chemically related to amphetamine. It is thought that the primary way phentermine works is by inducing a reducti...

    Drugs: Pyridoxal phosphate · Ademetionine · Ascorbic acid · Tyrosine · NADH · Phentermine +8 more
  3. Pathway

    Cocaine Norepinephrine Reuptake Inhibitor Action Pathway

    smpdb.ca/view/SMP0126544
    Drug action

    Cocaine inhibits the sodium-dependent noradrenaline channel which causes norepinephrine to accumulate in the synapse. … The high concentration of norepinephrine readily activates both alpha adrenergic receptors in the smooth muscles of blood vessels.

    Drugs: Pyridoxal phosphate · Ascorbic acid · Tyrosine · Norepinephrine · Cocaine · Dopamine +4 more
  4. Pathway

    Milnacipran SNRI - Norepinephrine reuptake Inhibition Action Pathway

    smpdb.ca/view/SMP0126429
    Drug action

    Milnacipran is a serotonin and norepinephrine reuptake inhibitor (SNRI). … Such NE pain mitigation is consequently also enhanced by milnacipran's ability to enhance the presence of NE by inhibiting its reuptake via norepinephrine transporters at synaptic clefts

    Drugs: Pyridoxal phosphate · Ascorbic acid · Tyrosine · Norepinephrine · Dopamine · Levodopa +4 more
  5. Pathway

    Levomilnacipran SNRI - Norepinephrine reuptake Inhibition Action Pathway

    smpdb.ca/view/SMP0126430
    Drug action

    Levomilnacipran (the more active 1S, 2R - enantiomer of milnacipran) is a serotonin and norepinephrine reuptake inhibitor (SNRI). … Such NE pain mitigation is consequently also enhanced by milnacipran's ability to enhance the presence of NE by inhibiting its reuptake via norepinephrine transporters at synaptic clefts

    Drugs: Pyridoxal phosphate · Ascorbic acid · Tyrosine · Norepinephrine · Dopamine · Levodopa +4 more
  6. Pathway

    Tranylcypromine Amine Oxidase Norepinephrine Antidepressant Action Pathway

    smpdb.ca/view/SMP0126672
    Drug action

    The first one is found in cells located in the periphery and breakdown serotonin, norepinephrine, epinephrine, dopamine, and tyramine. … The second one, the B isoform, breakdowns phenylethylamine, norepinephrine, epinephrine, dopamine, and tyramine. This isoform is found in the extracellular tissues and mostly in the brain.

    Drugs: Pyridoxal phosphate · Ademetionine · Ascorbic acid · Tyrosine · NADH · Sapropterin +8 more
  7. Pathway

    Phenelzine Amine Oxidase Norepinephrine Antidepressant Action Pathway

    smpdb.ca/view/SMP0126682
    Drug action

    The first one is found in cells located in the periphery and breakdown serotonin, norepinephrine, epinephrine, dopamine, and tyramine. … Phenelzine inhibits both isoforms causing an elevation in brain levels of catecholamines (like norepinephrine) and serotonin. This drug is administered as an oral tablet.

    Drugs: Pyridoxal phosphate · Ademetionine · Ascorbic acid · Tyrosine · NADH · Sapropterin +8 more
  8. Pathway

    Minaprine Amine oxidase Norepinephrine Antidepressant Action Pathway

    smpdb.ca/view/SMP0126684
    Drug action

    The first one is found in cells located in the periphery and breakdown serotonin, norepinephrine, epinephrine, dopamine, and tyramine. … The second one, the B isoform, breakdowns phenylethylamine, norepinephrine, epinephrine, dopamine, and tyramine. This isoform is found in the extracellular tissues and mostly in the brain.

    Drugs: Pyridoxal phosphate · Ademetionine · Ascorbic acid · Tyrosine · NADH · Sapropterin +8 more
  9. Pathway

    Moclobemide Amine Oxidase Norepinephrine Antidepressant Action Pathway

    smpdb.ca/view/SMP0126685
    Drug action

    The first one is found in cells located in the periphery and breakdown serotonin, norepinephrine, epinephrine, dopamine, and tyramine. … The second one, the B isoform, breakdowns phenylethylamine, norepinephrine, epinephrine, dopamine, and tyramine. This isoform is found in the extracellular tissues and mostly in the brain.

    Drugs: Pyridoxal phosphate · Ademetionine · Ascorbic acid · Tyrosine · NADH · Sapropterin +8 more
  10. Pathway

    Doxepin Norepinephrine Reuptake Inhibitor Action Pathway (New)

    smpdb.ca/view/SMP0126355
    Drug action

    Doxepin is a psychotropic agent with antidepressant and anxiolytic properties. It is used for the treatment of depression, anxiety, manic-depressive disorder, and insomnia. Similar to other tricyclic antidepressants, doxepin decreases th...

    Drugs: Pyridoxal phosphate · Ascorbic acid · Tyrosine · Tryptophan · Sapropterin · Norepinephrine +7 more