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Teniposide
go.drugbank.com/drugs/DB00444ApprovedInvestigationalAccumulated breaks in DNA prevent cells from entering into the mitotic phase of the cell cycle, and lead to cell death. Teniposide acts primarily in the G2 and S phases of the cycle. … Teniposide is a semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. Teniposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA.
Categories: Antineoplastic and Immunomodulating Agents, Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic IndexSynonyms: 4'-demethylepipodophyllotoxin 9-(4,6-O-(R)-2-thenylidene-beta-D-glucopyranoside)Dapiprazole
go.drugbank.com/drugs/DB00298ApprovedDapiprazole (U.S. trade name Rev-Eyes) is an alpha blocker. It is found in ophthalmic solutions used to reverse mydriasis after an eye examination.
Synonyms: 5,6,7,8-Tetrahydro-3-(2-(4-(o-tolyl)-1-piperazinyl)ethyl)-s-triazolo(4,3-a)pyridineCategories: Antiglaucoma Preparations and Miotics, Heterocyclic Compounds, 1-RingEsculin
go.drugbank.com/drugs/DB13155Approved) and in daphnin (the dark green resin of Daphne mezereum). … These are carbohydrate derivatives in which a sugar group is bonded through its anmoeric carbonA to another group via a C-, S-,N-,O-, or Se- glycosidic bond.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: Esculetin 6-O-glucoside, 6,7-Dihydroxycoumarin-6-O-glucosideEthyl salicylate
go.drugbank.com/drugs/DB15576ApprovedWithdrawnSynonyms: Ethyl o-hydroxybenzoate, Ethyl 2-hydroxybenzoateFenthion
go.drugbank.com/drugs/DB11412ExperimentalVet approvedFenthion is an _organothiophosphate_ drug used as an insecticide, avicide, and acaricide. … Fenthion is listed as a restricted use compound by the United States Environmental Protection Agency due to its potential to cause cholinesterase inhibition in humans and animals.
Categories: Compounds used in a research, industrial, or household settingSynonyms: O,O-Dimethyl O-4-methylthio-m-tolyl phosphorothioate, O,O-Dimethyl O-[3-methyl-4-(methylsulfanyl)phenyl] thiophosphateAzercabtagene zapreleucel
go.drugbank.com/drugs/DB17185InvestigationalSynonyms: Adult allogeneic CD4+ and CD8+ enriched T cells, gene edited through the electroporati, Adult allogeneic CD4+ and CD8+ enriched T cells transduced with an anti-CD19 chimeric antigen receptor (CAR) that is site-specific integrated into the cellular genome.Zifibancimig
go.drugbank.com/drugs/DB19332InvestigationalZifibancimig is under investigation in clinical trial NCT04567303, focusing on participants with neovascular age-related macular degeneration.
Synonyms: Immunoglobulin G1 Fab fragment, bispecific, anti-(human vascular endothelial growth factor A and angiopoietin 2) (human monoclonal RO7250284 γ1-chain), disulfide with human monoclonal RO7250284 κ-chain, mmunoglobulin Fab G1-kappa, anti-[Homo sapiens ANGPT2 (angiopoietin 2, Ang2)] and anti-[Homo sapiens VEGFA (vascular endothelial growth factor A, VEGF-A, VEGF), monoclonal antibody, bispecific, biparatope2,5-O,O-BIS-{4',4''-AMIDINOPHENYL}-1,4:3,6-DIANHYDRO-D-SORBITOL
go.drugbank.com/drugs/DB04792ExperimentalSynonyms: 2,5-O,O-BIS-{4',4''-AMIDINOPHENYL}-1,4:3,6-DIANHYDRO-D-SORBITOLSulfamic Acid 2,3-O-(1-Methylethylidene)-4,5-O-Sulfonyl-Beta-Fructopyranose Ester
go.drugbank.com/drugs/DB02894ExperimentalSynonyms: Sulfamic Acid 2,3-O-(1-Methylethylidene)-4,5-O-Sulfonyl-Beta-Fructopyranose EsterFamphur
go.drugbank.com/drugs/DB11408ExperimentalVet approvedSynonyms: O-[4-(dimethylsulfamoyl)phenyl] O,O-dimethyl thiophosphate, Phosphorothioic acid, O-(4-((dimethylamino)sulfonyl)phenyl) O,O-dimethyl esterCategories: Compounds used in a research, industrial, or household setting