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Zuclopenthixol
go.drugbank.com/drugs/DB01624ApprovedInvestigationalThese are organic polycyclic compounds containing a thioxanthene moiety, which is an aromatic tricycle derived from xanthene by replacing the oxygen atom with a sulfur atom. … It is known that zuclopenthixol is metabolized by Cytochrome P450 2D6. Zuclopenthixol was approved for use in Canada in 2011, but is not approved for use in the United States.
Products: CIATYL Z 10MG, CLOPIXOL 10MGPseudoephedrine
go.drugbank.com/drugs/DB00852ApprovedPseudoephedrine is structurally related to [ephedrine] but exerts a weaker effect on the sympathetic nervous system. … [A188820,A188823] Both drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and were first researched in the west in 1889.
Mixtures: IBUCOLD PLUS 100MG+15MG+1MG/5ML ŞURUP, 100 ML SISE, BENICAL 10 MG+20MG+2MG/5 ML SURUP, 100 MLCategories: Alpha-and Beta-adrenergic AgonistsVudalimab
go.drugbank.com/drugs/DB18833InvestigationalVudalimab is under investigation in clinical trial NCT05005728 (Xmab®20717 (Vudalimab) Alone or in Combination With Chemotherapy or Targeted Therapy in Patients With Metastatic Castration-resistant Prostate Cancer).
Synonyms: Immunoglobulin half-ig g1-kappa/scfv-h-ch2-ch3, anti-(homo sapiens ctla4 (cytotoxic t-lymphocyte-associated protein 4, cd152)) and anti-(homo sapienspdcd1 (programmed cell death 1, pd-1, pd1, cd279)),Loratadine
go.drugbank.com/drugs/DB00455ApprovedInvestigational[A176435] A lack of sedative and CNS adverse effects make loratadine, along with other second generation antihistamines, preferable over their 1st generation counterparts in many clinical situations.
Mixtures: LORATADINA 5MG/FENILEFRINA 15MG TABLETAS, Up and Up allergy and congestion reliefCategories: Loratadine and derivativesDoxorubicin
go.drugbank.com/drugs/DB00997ApprovedInvestigational[A257614] Thanks to its efficacy and broad effect, doxorubicin was approved by the FDA in 1974 to treat a variety of cancer, including but not limited to breast, lung, gastric, ovarian, thyroid, non-Hodgkin … Doxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius var. caesius along side with daunorubicin, another cytotoxic agent, in 1970.
Categories: Anthracyclines and Related Substances, Antineoplastic and Immunomodulating AgentsProducts: A.D. Mycin injection 2mg/ml, ADRIMEDAC 10MG (2MG/ML)Propranolol
go.drugbank.com/drugs/DB00571ApprovedInvestigational[L6904] Propranolol is used to treat a number of conditions but most commonly is used for hypertension.[L6901,L6904,L6907] Propranolol was granted FDA approval on 13 November 1967.[L6904]
Mixtures: Propranolol Hydrochloride and Hydrochlorothiazide, Propranolol Hydrochloride and HydrochlorothiazideCategories: propranolol and thiazides, Beta Blocking Agents and ThiazidesHydrocortisone
go.drugbank.com/drugs/DB00741ApprovedInvestigationalVet approved[L10529,L10532,L10535,L10538,L7772,L7321] It was discovered in the 1930s by Edward Kendall and named Compound F, or 17-hydroxycorticosterone. … Hydrocortisone, or cortisol, is a glucocorticoid secreted by the adrenal cortex.[A188387] Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions.
Mixtures: Ti-U-lac HC Lotion, Neomycin and Polymyxin B Sulfates and HydrocortisoneCategories: Alimentary Tract and Metabolism, Sex Hormones and InsulinsCodeine
go.drugbank.com/drugs/DB00318ApprovedIllicitInvestigationalCodeine, an opioid analgesic, was originally approved in the US in 1950 and is a drug used to decrease pain by increasing the threshold for pain without impairing consciousness or altering other sensory … Opiates such as codeine are derived from the poppy plant, _Papaver somniferum_ (Papaveraceae).
Mixtures: TALVOSILEN 500/20MG, A & C Tablets With Codeine 15mgCategories: Cough and Cold Preparations, codeine and ibuprofenThioridazine
go.drugbank.com/drugs/DB00679ApprovedWithdrawnThioridazine has a higher incidence of antimuscarinic effects, but a lower incidence of extrapyramidal symptoms, than chlorpromazine. (From Martindale, The Extra Pharmacopoeia, 30th ed, p618). … A phenothiazine antipsychotic used in the management of psychoses, including schizophrenia, and in the control of severely disturbed or agitated behavior. It has little antiemetic activity.
Products: Novo-ridazine 25mg, Mellaril Tab 25mgLeflunomide
go.drugbank.com/drugs/DB01097ApprovedInvestigationalLeflunomide was approved by FDA and in many other countries (e.g., Canada, Europe) in 1999. … Leflunomide is a pyrimidine synthesis inhibitor belonging to the DMARD (disease-modifying antirheumatic drug) class of drugs, which are chemically and pharmacologically very heterogeneous.
Categories: Leflunomide and metabolite, Antineoplastic and Immunomodulating AgentsProducts: ARAVA 20MG, LERADA® 20MG