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Fentanyl
go.drugbank.com/drugs/DB00813ApprovedIllicitInvestigationalVet approvedFentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia. … [A179542] In 2017, 47600 overdose deaths in the United States involved some opioid (over 2/3 of all overdose deaths).[L6748] Opioid overdoses kill an average of 11 Canadians daily.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: N-(1-phenethylpiperidin-4-yl)-N-phenylpropionamide, N-(1-Phenethyl-piperidin-4-yl)-N-phenyl-propionamideAzelaic acid
go.drugbank.com/drugs/DB00548ApprovedInvestigationalAzelaic acid is effective against a number of skin conditions, such as mild to moderate acne, when applied topically in a cream formulation of 20%. … It works in part by stopping the growth of skin bacteria that cause acne, and by keeping skin pores clear.
Mixtures: Azelaic Acid 15% / Niacinamide 4%, 2% Salicylic Acid FACIAL CLEANSERSynonyms: n-nonanedioic acidOxytetracycline
go.drugbank.com/drugs/DB00595ApprovedInvestigationalVet approvedA tetracycline analog isolated from the actinomycete streptomyces rimosus and used in a wide variety of clinical conditions.
Mixtures: HEKSA 30 MG/G + 10000 I.U./G MERHEM, POLIMISIN GÖZ MERHEMI, 3,5 GCategories: Genito Urinary System and Sex HormonesGuaifenesin
go.drugbank.com/drugs/DB00874ApprovedInvestigationalVet approvedAfter the negotiation between FDA and major manufacturers, a voluntary transition of labels for not using guaifenesin in children under the age of 4 years was endorsed by FDA in 2008 [F4525]. … to be safe and effective in children under the age of 6 years [F4525].
Mixtures: BROKSIN 6.66 MG/5 ML+100 MG/5 ML SURUP, 150 ML, SUDAFED EKSPEKTORAN 30 MG+100 MG/5 ML ŞURUP, 150 MLInternational brands: Duratuss GFluconazole
go.drugbank.com/drugs/DB00196ApprovedInvestigationalIt was initially approved by the FDA in 1990. This drug is an _azole_ antifungal, in the same drug family as [ketoconazole] and [itraconazole]. … Fluconazole, commonly known as _Diflucan_, is an antifungal drug used for the treatment of both systemic and superficial fungal infections in a variety of tissues.
Mixtures: GOTLAND CANDILOX 500/ 37.5 MG TABLETAS CUBIERTAS, FLUCONAZOL+SECNIDAZOL 75MG/1000 MGCategories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP2C9 InhibitorsMedroxyprogesterone acetate
go.drugbank.com/drugs/DB00603ApprovedInvestigationalMedroxyprogesterone acetate (MPA) is a [progesterone] derivative that is more resistant to metabolism for improved pharmacokinetic properties.
Mixtures: DIVICONT TABLETAS 1 MG/5 MG, DIVINA 2 MG + 2 MG /10 MG TABLET, 21 ADETCategories: Genito Urinary System and Sex Hormones, Sex Hormones and Modulators of the Genital SystemTirofiban
go.drugbank.com/drugs/DB00775ApprovedInvestigationalTirofiban prevents the blood from clotting during episodes of chest pain or a heart attack, or while the patient is undergoing a procedure to treat a blocked coronary artery. … It is a non-peptide reversible antagonist of the platelet glycoprotein (GP) IIb/IIIa receptor, and inhibits platelet aggregation.
Synonyms: N-(Butylsulfonyl)-O-(4-(4-piperidyl)butyl)-L-tyrosine, (2S)-2-(butylsulfonylamino)-3-[4-(4-piperidin-4-ylbutoxy)phenyl]propanoic acidProducts: AGREDUR READY 50 MCG/ML I.V. İNFÜZYON İÇİN ÇÖZELTİ, 250 ML, MULTİFLEX TİROSEL 50 MCG/ML İ.V. INFÜZYON İÇİN ÇÖZELTİ, 250 MLRifamycin
go.drugbank.com/drugs/DB11753ApprovedInvestigationalWithdrawnProduct which allowed it to have a status a priority review. … [A39986] Rifamycin was further developed by Cosmo Technologies Ltd and approved in November 16, 2018 by the FDA as a prescription drug after being granted the designation of Qualified Infectious Disease
Mixtures: RIFETEM 250 MG / 3 ML AMPUL, 50 ADET, RİF 250 MG/3 ML IM ENJEKSİYONLUK ÇÖZELTİ (100 AMPUL)Categories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 CYP1A2 InhibitorsNandrolone decanoate
go.drugbank.com/drugs/DB08804ApprovedIllicitInvestigational[A233849] Nandrolone decanoate was granted FDA approval on 5 October 1962.[L32564] … [A233789,A233849,L32564,L9464] The process for creating esters of [nandrolone] was patented in Spain in 1959[L33244] and in 1960, it was described as having a long duration of action and strong anabolic
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesProducts: DECA - DURABOLIN® 50 MG, Deca-Durabolin 50 mg/ml InjektionslösungEthionamide
go.drugbank.com/drugs/DB00609ApprovedInvestigationalWithdrawnA second-line antitubercular agent that inhibits mycolic acid synthesis. It also may be used for treatment of leprosy. (From Smith and Reynard, Textbook of Pharmacology, 1992, p868)
Categories: Heterocyclic Compounds, 1-RingSynonyms: 2-ethyl-4-thiopyridylamide, 2-ethylthioisonicotinamide