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Hypochlorite
go.drugbank.com/drugs/DB11123ApprovedInvestigationalHypochlorite is an ion composed of chlorine and oxygen with the chemical formula ClO−. … Hypochlorite is often used as a chemical reagent for chlorination and oxidation reactions.
Products: Eusol-Max 0.75% Antiseptic SolutionNitroglycerin
go.drugbank.com/drugs/DB00727ApprovedInvestigationalNitroglycerin, also known as glyceryl trinitrate,[A180169] is an organic nitrate and a vasodilating agent [L38369] that was first discovered in 1847. … [A180166,A180172] Its use as a treatment for angina dates back to 1879 and is still used to treat and prevent angina.[A249970] Nitroglycerin causes vasodilation in both arteries and veins.
Categories: Agents for Treatment of Hemorrhoids and Anal Fissures for Topical UseProducts: NITROGLICERINA PH&T, GLYDEX IV Solution for Injection 1mg/mlOlopatadine
go.drugbank.com/drugs/DB00768ApprovedAn ophthalmic solution of olopatadine was approved by the FDA and European Union for the treatment of seasonal and perennial allergic conjunctivitis in 1996 and 2002, respectively. … [A179809] Olopatadine is used for the symptomatic treatment of ocular itching associated with allergic conjunctivitis in ophthalmic formulations and seasonal allergic rhinitis in intranasal formulations
Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesProducts: OLOPA-MAC, OLODINA PF®Nivolumab
go.drugbank.com/drugs/DB09035ApprovedInvestigationalNivolumab is a fully human IgG4 antibody targeting the immune checkpoint programmed death receptor-1 (PD-1). … [L12129] This antibody was produced entirely in mice and grafted onto human kappa and IgG4 Fc region with the mutation _S228P_ for additional stability and reduced variability.
Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitors, PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitorsProducts: OPDIVO CONCENTRATE FOR SOLUTION FOR INFUSION 10 MG/ML, Opdivo 10mg/ml, Concentrate for solution for infusionLevosimendan
go.drugbank.com/drugs/DB00922ApprovedInvestigationalWithdrawnLevosimendan increases calcium sensitivity to myocytes by binding to troponin C in a calcium dependent manner. This increases contractility without raising calcium levels. It also relaxes vascular smooth muscle by opening adenosine triph...
Products: SIMDAX 2.5 MG/ML CONCENTRATE FOR SOLUTION FOR INFUSION, Simdax 2.5 mg/ml concentrate for solution for infusion.Ezetimibe
go.drugbank.com/drugs/DB00973ApprovedInvestigationalessential role in promoting intestinal cholesterol uptake via an ezetimibe-sensitive pathway. … [A15202] Ezetimibe is used as an adjunctive therapy to a healthy diet to lower cholesterol levels in primary hyperlipidemia, mixed hyperlipidemia, homozygous familial hypercholesterolemia (HoFH), and homozygous
Categories: Hypolipidemic Agents Indicated for Hyperlipidemia, Non-statin Hypolipidemic Agents Indicated for HyperlipidemiaProducts: Mar-ezetimibe, Mac-Zet (Ezetimibe Tablets USP 10 mg)Alfuzosin
go.drugbank.com/drugs/DB00346ApprovedThe prevalence of BPH is as high as 50%-60% for males in their 60's, and this prevalence increases to 80%-90% of those over 70. … Benign prostatic hyperplasia (BPH) refers to a benign growth or hyperplasia of the prostate and leads to lower urinary tract symptoms in men, such as urgency, frequency and changes to urine flow.
Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesProducts: Teva-alfuzosin Pr, Alfuzosin PH&T 10mg prolonged-release tabletsEletriptan
go.drugbank.com/drugs/DB00216ApprovedInvestigationalEletriptan is a second generation triptan drug developed by Pfizer Inc for the treatment of migraine headaches.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: Eletriptan HBR, RELERTAzithromycin
go.drugbank.com/drugs/DB00207ApprovedInvestigationalIt is primarily used for the treatment of respiratory, enteric and genitourinary infections and may be used instead of other macrolides for some sexually transmitted and enteric infections. … is a part of the _azalide_ subclass of macrolides, and contains a 15-membered ring, with a methyl-substituted nitrogen instead of a carbonyl group at the 9a position on the aglycone ring, which allows for
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: Mar-azithromycin, AZITHROMYCIN HEC P 200/5MLAfatinib
go.drugbank.com/drugs/DB08916ApprovedInvestigationalby an FDA-approved test [L2939]. … For oral use, afatinib tablets are a first-line (initial) treatment for patients with metastatic non-small cell lung cancer (NSCLC) with common epidermal growth factor receptor (EGFR) mutations as detected
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: Mar-afatinib