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Displaying results 1991 - 2000 of 5504 in total
  1. Drug

    Gabapentin enacarbil

    go.drugbank.com/drugs/DB08872
    Approved

    It is a prodrug of gabapentin, and indicated in adults for the treatment of Restless Legs Syndrome (RLS) and postherpetic neuralgia (PHN).

  2. Drug

    Lumacaftor

    go.drugbank.com/drugs/DB09280
    ApprovedInvestigational

    Consequently, lumacaftor increases successful production of CFTR ion channels and the total number of receptors available for use at the cell membrane for fluid and ion transport. … lung function (ppFEV1) were found to be statistically significant, but minimal, with only a 2.6-3.0% change from baseline with more than 70% of patients failing to achieve an absolute improvement of at

  3. Drug

    Beractant

    go.drugbank.com/drugs/DB06761
    Approved

    It is suspended in 0.9% sodium chloride solution, and heat-sterilized. … Considered a natural source of surfactant as it is made from bovine lung extract, beractant contains a mixture of phospholipids, neutral lipids, fatty acids, and surfactant-associated proteins such as

  4. Drug

    Eugenol

    go.drugbank.com/drugs/DB09086
    ApprovedInvestigational

    Its exact mechanism of action is unknown, however, it has been shown to interfere with action potential conduction. … It has been used as a topical antiseptic as a counter-irritant and in dental preparations with zinc oxide for root canal sealing and pain control.

  5. Drug

    Aceclidine

    go.drugbank.com/drugs/DB13262
    Approved

    [A274273] It has also been studied in the treatment of presbyopia, a common age-related vision loss where the crystalline lens hardens and loses elasticity, impairing near vision.

  6. Drug

    Clostridium tetani toxoid antigen (formaldehyde inactivated)

    go.drugbank.com/drugs/DB10583
    ApprovedInvestigational

    It is used for active immunization of children 7 years of age or older, and adults, for prevention of tetanus.

    Mixtures: Dt Polio Adsorbed - Sus Im, Bio Farma Adsorbed DT VaccineProducts: TT Vaccine, VAKSIN TT
  7. Drug

    Influenza B virus B/Utah/9/2014 antigen (MDCK cell derived, propiolactone inactivated)

    go.drugbank.com/drugs/DB11002
    ApprovedWithdrawn

    This defence includes the production of humoral immunity through the development of antibodies (through memory B cells) and of cell-mediated immunity through the production of T-lymphocytes. … re-exposure to infectious influenza virus, the immune system is prepared to identify and destroy the virus as there are circulating antibodies that recognize that particular component of the virus that it

    Mixtures: Medical Provider Single Use EZ Flu Shot 2018-2019, Medical Provider Single Use EZ Flu Shot Flucelvax 2015-2016
  8. Drug

    Potassium gluconate

    go.drugbank.com/drugs/DB13620
    Approved

    It is the most abundant cation in the intracellular fluid, where it plays a key role in maintaining cell function [A32222]. … It is also used as a potassium supplement [L2657]. Potassium is an essential nutrient.

  9. Drug

    Arimoclomol

    go.drugbank.com/drugs/DB05025
    Approved

    [L51384] Arimoclomol was approved by the FDA on September 20, 2024, making it the first treatment for Niemann-Pick disease, type C (NPC). … [L51389] It is also being investigated in amyotrophic lateral sclerosis (ALS) [A264414, A264429] and inclusion body myositis.[A264419]

  10. Drug

    Isoflurophate

    go.drugbank.com/drugs/DB00677
    ApprovedWithdrawn

    (From Martindale, The Extra Pharmacopoeia, 29th ed, p1330) … It is a powerful miotic used mainly in the treatment of glaucoma. Its vapor is highly toxic and it is recommended that only solutions in arachis oil be used therapeutically.