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Spiramycin
go.drugbank.com/drugs/DB06145ApprovedInvestigationalWithdrawnSpiramycin is a 16-membered ring macrolide discovered in 1952 as a product of Streptomyces ambofaciens that has been available in oral formulations since 1955, and parenteral formulations since 1987. … of spirochetes, Toxoplasma gondii and Cryptosporidium.
Mixtures: METİRASİN 1,5 MIU/250 MG FILM TABLET, 14 ADET, METİRASİN 1,5 MIU/250 MG FİLM KAPLI TABLET, 10 ADETSynonyms: Foromacidin A, Spiramycin AEtonogestrel
go.drugbank.com/drugs/DB00294ApprovedInvestigationalEtonogestrel molecule is a 3-ketodesogestrel or 19-nortestosterone which is a synthetic biologically active metabolite of progestin desogestrel.
Mixtures: NUVARING VAGINAL HALKA, 1 ADETCategories: Sex Hormones and Modulators of the Genital SystemSaw palmetto
go.drugbank.com/drugs/DB14360ApprovedSaw palmetto is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Mixtures: PROSTAGOOD PLUS KAPSÜL, 120 ADET, PROSTAGOOD PLUS KAPSÜL, 60 ADETProducts: PROSTAGOOD MONO KAPSUL, 120 ADET, PROSTAGOOD MONO KAPSUL, 60 ADETLenalidomide
go.drugbank.com/drugs/DB00480ApprovedInvestigationalcontain an imide group. … Lenalidomide (previously referred to as CC-5013) is an immunomodulatory drug with potent antineoplastic, anti-angiogenic, and anti-inflammatory properties.
Products: LENALIDOMIDE SUN, RELİV 5 MG SERT KAPSÜL, 21 ADETTegafur
go.drugbank.com/drugs/DB09256ApprovedInvestigationalTegafur (INN, BAN, USAN) is a prodrug of [DB00544] (5-FU), an antineoplastic agent used as the treatment of various cancers such as advanced gastric and colorectal cancers. … It is a pyrimidine analogue used in combination therapies as an active chemotherapeutic agent in conjunction with [DB09257] and [DB03209], or along with [DB00544] as [DB09327].
International brands: ESUEEW AN T, Ai YiCategories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2A6 Substrates with a Narrow Therapeutic IndexAgmatine
go.drugbank.com/drugs/DB08838ExperimentalUp to now (July 2013), the results of this study have not yet been published. … Agmatine is both an experimental and investigational drug.
Ibrutinib
go.drugbank.com/drugs/DB09053ApprovedInvestigationalIbrutinib is a small molecule that acts as an irreversible potent inhibitor of Burton's tyrosine kinase. … It is designated as a targeted covalent drug and presented as a promising activity in B-cell malignancies in clinical trials.
Products: IMBRUVİCA 140 MG FİLM KAPLI TABLET, 30 ADET, IMBRUVİCA 280 MG FİLM KAPLI TABLET, 30 ADETBazedoxifene
go.drugbank.com/drugs/DB06401ApprovedInvestigationalBazedoxifene is a third generation selective estrogen receptor modulator (SERM), developed by Pfizer following the completion of their takeover of Wyeth Pharmaceuticals. … In late 2013, Pfizer received approval for bazedoxifene as part of the combination drug DUAVEE in the prevention (not treatment) of postmenopausal osteoporosis.
Categories: Sex Hormones and Modulators of the Genital SystemCeritinib
go.drugbank.com/drugs/DB09063ApprovedInvestigationalAbout 4% of patients with NSCLC have a chromosomal rearrangement that generates a fusion gene between EML4 (echinoderm microtubule-associated protein-like 4) and ALK (anaplastic lymphoma kinase), which … This occurrence led to development of novel second-generation ALK inhibitors such as ceritinib to overcome crizotinib resistance.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: ZYKADIA 150 MG KAPSÜL, 150 ADETInfigratinib
go.drugbank.com/drugs/DB11886ApprovedInvestigationalWithdrawn[A198963] Infitratinib is a pan-FGFR inhibitor, as it is an ATP-competitive inhibitor of all four FGFR receptor subtypes. … Infigratinib is a pan-fibroblast growth factor receptor (FGFR) kinase inhibitor.