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Rolitetracycline
go.drugbank.com/drugs/DB01301ApprovedWithdrawnA pyrrolidinylmethyl tetracycline.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseActivated charcoal
go.drugbank.com/drugs/DB09278ApprovedInvestigationalActivated charcoal, or activated carbon, is an amorphous form of carbon prepared from incomplete combustion of carbonaceous organic matter. … It is activated by an oxidizing gas flow at high temperature passed over its surface to make a fine network of pores, producing a material with large surface area and high affinity for various substances
Categories: Compounds used in a research, industrial, or household settingPemigatinib
go.drugbank.com/drugs/DB15102ApprovedInvestigationalWith increasing research on the pathogenesis of cholangiocarcinoma and potential therapeutic targets for anticancer drug treatment, recent studies show that up to 45% of patients with intrahepatic cholangiocarcinoma … This malignancy accounts for 15% to 20% of primary hepatobiliary malignancies, which account for 13% of overall cancer-related global mortality.
Edotreotide gallium Ga-68
go.drugbank.com/drugs/DB15494Approved[L8603] Edotreotide gallium Ga-68 is indicated for localizing somatostatin receptor positive neuroendocrine tumors by positron emission tomography. … [L8597] [Dotatate gallium Ga-68] is used for a similar indication.[A185852] Dotatate gallium Ga-68 has lower tumor uptake but this data is highly variable between patients.
Sulconazole
go.drugbank.com/drugs/DB06820ApprovedSulconazole nitrate, the active ingredient, is an imidazole derivative that inhibits the growth of common pathogenic dermatophytes, making it an effective treatment for tinea cruris and tinea corporis
Categories: Antifungals for Topical Use, Antifungals for Dermatological UseTiludronic acid
go.drugbank.com/drugs/DB01133ApprovedVet approvedWithdrawn[A1923] Tiludronic acid was first described in the literature in 1988 as a potential treatment for Paget's disease of bone.[A202235] Tiludronic acid was granted FDA approval on 7 March 1997.[L4763] … Tiludronate, or (4-chlorophenyl)thio-methylene-1,1-bisphosphonate, is a first generation bisphosphonate similar to [etidronic acid] and [clodronic acid].
Categories: Drugs for Treatment of Bone DiseasesLasmiditan
go.drugbank.com/drugs/DB11732ApprovedInvestigationalsuitable for use in patients with pre-existing cardiovascular disorders. … [A187316,A187322] Lasmiditan, in contrast, is a highly selective agonist of 5-HT<sub>1F</sub> receptors, carrying virtually no affinity for other receptors which appear to be largely responsible for
Pepsin
go.drugbank.com/drugs/DB13198ApprovedWithdrawnPepsin is often used as a replacement enzyme for those with pancreatic insufficiency [L2357]. … Any changes or conditions affecting metabolic steps for successful digestion and absorption negatively affect pancreatic enzymatic secretion, entry into the intestine, functionality once inside the intestine
Estradiol valerate
go.drugbank.com/drugs/DB13956ApprovedInvestigationalVet approveddue to menopause, for the treatment of hypoestrogenism due to hypogonadism, castration or primary ovarian failure, and for the treatment of advanced androgen-dependent carcinoma of the prostate (for palliation … As a pro-drug of estradiol, estradiol acetate therefore has the same downstream effects within the body through binding to the Estrogen Receptor (ER) including ERα and ERβ subtypes, which are located in
Categories: Hormonal Contraceptives for Systemic UseDimercaprol
go.drugbank.com/drugs/DB06782ApprovedIn addition, it has in the past been used for the treatment of Wilson's disease, a genetic disorder in which the body tends to retain copper.
Categories: Compounds used in a research, industrial, or household setting