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Displaying results 2051 - 2060 of 10000 in total
  1. Pathway

    Trisalicylate-Choline Action Pathway

    smpdb.ca/view/SMP0000703
    Drug action

    Decreased prostaglandin synthesis in many animal model's cell is caused by presence of trisalicylate-choline. … Prostaglandin G/H synthase 1 and 2 catalyze the arachidonic acid to prostaglandin G2, and also catalyze prostaglandin G2 to prostaglandin H2 in the metabolism pathway.

    Drugs: Glutamic acid · Glutathione · Dinoprostone · Calcium · Magnesium cation · Choline magnesium trisalicylate +5 more
    Enzymes: Prostaglandin E synthase
  2. Pathway

    Tenoxicam Action Pathway

    smpdb.ca/view/SMP0000706
    Drug action

    Decreased prostaglandin synthesis in many animal model's cell is caused by presence of tenoxicam. … Prostaglandin G/H synthase 1 and 2 catalyze the arachidonic acid to prostaglandin G2, and also catalyze prostaglandin G2 to prostaglandin H2 in the metabolism pathway.

    Drugs: Glutamic acid · Glutathione · Tenoxicam · Dinoprostone · Calcium · Magnesium cation +5 more
    Enzymes: Prostaglandin E synthase
  3. Pathway

    Salicylic Acid Action Pathway

    smpdb.ca/view/SMP0000709
    Drug action

    Decreased prostaglandin synthesis in many animal model's cell is caused by presence of Salicylic acid. … Prostaglandin G/H synthase 1 and 2 catalyze the arachidonic acid to prostaglandin G2, and also catalyze prostaglandin G2 to prostaglandin H2 in the metabolism pathway.

    Drugs: Glutamic acid · Glutathione · Dinoprostone · Salicylic acid · Calcium · Magnesium cation +5 more
    Enzymes: Prostaglandin E synthase
  4. Pathway

    Acetaminophen Action Pathway

    smpdb.ca/view/SMP0000710
    Drug action

    Decreased prostaglandin synthesis in many animal model's cell is caused by presence of acetaminophen. … Prostaglandin G/H synthase 1 and 2 catalyze the arachidonic acid to prostaglandin G2, and also catalyze prostaglandin G2 to prostaglandin H2 in the metabolism pathway.

    Drugs: Glutamic acid · Glutathione · Acetaminophen · Dinoprostone · Calcium · Magnesium cation +5 more
    Enzymes: Prostaglandin E synthase
  5. Drug

    Tagraxofusp

    go.drugbank.com/drugs/DB14731
    ApprovedInvestigational

    a myeloid malignancy in the dendritic cell lineage. … It is a fusion protein composed of a human interleukin-3 (IL-3) that is genetically fused to the catalytic and translocation domains of truncated diphtheria toxin (DT) produced in _Escherichia coli_.

    Synonyms: Diphtheria toxin-il-3 fusion protein targeting IL-3 receptor
  6. Drug

    Technetium Tc-99m pyrophosphate

    go.drugbank.com/drugs/DB09165
    Approved

    A radionuclide imaging agent used primarily in scintigraphy or tomography of the heart to evaluate the extent of the necrotic myocardial process. … It has also been used in noninvasive tests for the distribution of organ involvement in different types of amyloidosis and for the evaluation of muscle necrosis in the extremities.

    Categories: Compounds used in a research, industrial, or household setting
  7. Drug

    Polidocanol

    go.drugbank.com/drugs/DB06811
    ApprovedInvestigational

    Polidocanol is a sclerosing agent indicated to treat uncomplicated spider veins (varicose veins ≤1 mm in diameter) and uncomplicated reticular veins (varicose veins 1 to 3 mm in diameter) in the lower … The formula for Polidocanol has the structural formula C12H25(OCH2CH2)nOH, a mean extent of polymerization (n) of approximately 9 and a mean molecular weight of approximately 600.

    Mixtures: DENTINOX 3.4 MG/G + 3.2 MG/G + 150 MG/G JEL, 10 G, DENTINOX 3.4 MG/G + 3.2 MG/G + 150 MG/G JEL, 20 GCategories: Compounds used in a research, industrial, or household setting
  8. Drug

    Iberdomide

    go.drugbank.com/drugs/DB12101
    Investigational

    at least one prior line of therapy including a proteasome inhibitor and an immunomodulatory agent. … [L64055,L64056] It is the first cereblon E3 ligase modulator (CELMoD) approved for multiple myeloma.[L64057]

    Categories: Cereblon E3 ligase modulator, Cytochrome P-450 SubstratesSynonyms: (S)-3-(4-((4-(Morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione, 2,6-Piperidinedione, 3-(1,3-dihydro-4-((4-(4-morpholinylmethyl)phenyl)methoxy)-1-oxo-2H-isoindol-2-yl)-, (3S)-
  9. Drug

    Torasemide

    go.drugbank.com/drugs/DB00214
    ApprovedInvestigational

    Torasemide is a high-ceiling loop diuretic.[A174463] Structurally, it is a pyridine-sulfonylurea used as an antihypertensive agent. … [A319] Torasemide was first approved for clinical use by the FDA in 1993.[L5257]

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingSynonyms: N-(((1-Methylethyl)amino)carbonyl)-4-((3-methylphenyl)amino)-3-pyridinesulfonamide, 1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea
  10. Drug

    N-Acetylglucosamine

    go.drugbank.com/drugs/DB00141
    ApprovedInvestigationalNutraceutical

    The N-acetyl derivative of glucosamine.

    Mixtures: Iris Ink Eye Drops, Iris Ink Eye DropsSynonyms: N-Acetyl-D-glucosamine, aldehydo-N-acetyl-D-glucosamine