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Letermovir
go.drugbank.com/drugs/DB12070ApprovedInvestigationalLetermovir recieved approval from the FDA on November 8th, 2017 for use in prophylaxis of cytomegalovirus (CMV) infection in allogeneic hematopoietic stem cell transplant patients.
Barium sulfate
go.drugbank.com/drugs/DB11150ApprovedBarium sulfate is an inorganic compound with the chemical formula BaSO4 [L1957]. Barium sulfate occurs in nature as the mineral _barite_. … It is also used in various manufacturing applications and mixed into heavy concrete to serve as a radiation shield [L1957]. This drug is used as a contrast agent in diagnostic x-ray procedures.
Mixtures: E-Z HD SULFATODE BARIO PARA SUSPENSION, E-Z HD SULFATODE BARIO PARA SUSPENSIONCategories: Compounds used in a research, industrial, or household setting, X-Ray Contrast Media, Non-IodinatedBovine type I collagen
go.drugbank.com/drugs/DB10771ApprovedInvestigationalIt plays a vital role in cell growth, differentiation, attachment, and migration [L2481]. … Bovine collagen alpha-1 is a naturally occurring extracellular matrix protein which is found in tendons and other connective tissues.
Dexfenfluramine
go.drugbank.com/drugs/DB01191ApprovedIllicitWithdrawnFor a fairly limited time during the middle of the nineties, the US FDA had approved it for use in managing weight loss.
Synonyms: d-N-ethyl-α-methyl-m-trifluoromethylphenethylamine, (S)-N-ethyl-1-[3-(trifluoromethyl)phenyl]propan-2-amineAxitinib
go.drugbank.com/drugs/DB06626ApprovedInvestigational[L6676] Axitinib is an indazole derivative.[A179398] It is most commonly marketed under the name Inlyta® and is available in oral formulations.
Synonyms: N-methyl-2-[[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfanyl]benzamideMexazolam
go.drugbank.com/drugs/DB15489Investigational[A184910] The use of benzodiazepines in the treatment of anxiety is generally a second line measure.[A184910]
Insulin degludec
go.drugbank.com/drugs/DB09564ApprovedInvestigational[A18561,A18562,A18563,A18564,A174934] Compared to available long-acting analogs such as [DB00047] and [DB01307], which have a duration of action of 20-24 hours, insulin degludec provides a consistent level … damage has been caused to pancreatic cells that the body is no longer able to produce insulin on its own.
Mixtures: Xultophy Pre-filled PenCategories: Drugs Used in DiabetesVorinostat
go.drugbank.com/drugs/DB02546ApprovedInvestigationalIt is the first in a new class of agents known as histone deacetylase inhibitors. … A recent study suggested that vorinostat also possesses some activity against recurrent glioblastoma multiforme, resulting in a median overall survival of 5.7 months (compared to 4 - 4.4 months in earlier
Lomitapide
go.drugbank.com/drugs/DB08827ApprovedUnlike traditional statin therapy, which relies on the upregulation of LDL receptors to clear cholesterol, Lomitapide acts independently of the LDL receptor by preventing the assembly and secretion of … Lomitapide, marketed under the brand names Juxtapid (USA) and Lojuxta (EU), is a first-in-class, small-molecule inhibitor of microsomal triglyceride transfer protein (MTP).
Categories: Non-statin Hypolipidemic Agents Indicated for HyperlipidemiaSynonyms: 9H-FLUORENE-9-CARBOXAMIDE, N-(2,2,2-TRIFLUOROETHYL)-9-(4-(4-(((4'-(TRIFLUOROMETHYL)(1,1'-BIPHENYL)-2-YL)CARBONYL)AMINO)-1-PIPERIDINYL)BUTYL)-, N-(2,2,2-TRIFLUOROETHYL)-9-(4-(4-(((4'-(TRIFLUOROMETHYL)BIPHENYL-2-YL)CARBONYL)AMINO)PIPERIDIN-1-YL)BUTYL)-9H-FLUORENE-9-CARBOXAMIDEDihydrocodeine
go.drugbank.com/drugs/DB01551ApprovedIllicitIt was marketed in 1911. … Dihydrocodeine is an opioid analgesic used as an alternative or adjunct to codeine to treat moderate to severe pain, severe dyspnea, and cough.
Mixtures: Poly-tussin EXProducts: PARACODIN N, PARACODIN N TROPFEN